p-Bromophenyl 2-chloroethyl sulfone

Base Information

• Chemical Name: p-Bromophenyl 2-chloroethyl sulfone
• CAS No.: 26732-25-2
• Molecular Formula: C8H8 Br Cl O2 S
• Molecular Weight: 283.573
• Hs Code.: 2904909090
• NSC Number: 202564
• UNII: DCG5L9RB6C
• DSSTox Substance ID: DTXSID60181243
• Nikkaji Number: J48.749J
• Wikidata: Q83051851
• Mol file: 26732-25-2.mol

Synonyms:26732-25-2;p-Bromophenyl 2-chloroethyl sulfone;1-bromo-4-(2-chloroethylsulfonyl)benzene;1-bromo-4-[(2-chloroethyl)sulfonyl]benzene;1-Bromo-4-[(2-chloroethane)sulfonyl]benzene;Sulfone, p-bromophenyl 2-chloroethyl;1-bromo-4-(2-chloroethanesulfonyl)benzene;1-Bromo-4-((2-chloroethyl)sulfonyl)benzene;Benzene, 1-bromo-4-[(2-chloroethyl)sulfonyl]-;MFCD01124703;NSC-202564;Benzene, 1-bromo-4-((2-chloroethyl)sulfonyl)-;NSC 202564;BRN 2270062;DCG5L9RB6C;3-06-00-01048 (Beilstein Handbook Reference);SCHEMBL3514586;DTXSID60181243;BSSDAMWQINGNMC-UHFFFAOYSA-N;sulfone,p-bromophenyl2-chloroethyl;BBA73225;NSC202564;STL370401;AKOS008965633;NS-04706;CS-0213099;1-Bromo-4-(2-chloro-ethanesulfonyl)-benzene;EN300-09255;Z56346909

Chemical Property of p-Bromophenyl 2-chloroethyl sulfone

Chemical Property:

• Vapor Pressure: 2.94E-06mmHg at 25°C
• Boiling Point: 400.4°Cat760mmHg
• Flash Point: 196°C
• PSA: 42.52000
• Density: 1.617g/cm³
• LogP: 3.54240
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 281.91169
• Heavy Atom Count: 13
• Complexity: 239

Purity/Quality:

99% ^*data from raw suppliers

1-Bromo-4-((2-chloroethyl)sulfonyl)benzene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1S(=O)(=O)CCCl)Br

Technology Process of p-Bromophenyl 2-chloroethyl sulfone

There total 3 articles about p-Bromophenyl 2-chloroethyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethene (74-85-1) + 4-bromobenzenesulfonyl chloride (98-58-8) → 1-bromo-4-(2-chloroethylsulfonyl)benzene (26732-25-2)

Guidance literature:

With triethylamine hydrochloride; copper dichloride; In dichloromethane; acetonitrile; at 140 ℃; for 12h;

DOI:10.1039/P19720001543

Reference yield:

4-bromo-benzenesulfinic acid (1195-33-1) + 2-chloro-ethanol (107-07-3) → 1-bromo-4-(2-chloroethylsulfonyl)benzene (26732-25-2)

Guidance literature:

With potassium hydroxide; at 100 - 120 ℃; Behandeln des Reaktionsprodukts mit PCl₅;

DOI:10.1039/jr9330000046

Reference yield:

→ 1-bromo-4-(2-chloroethylsulfonyl)benzene (26732-25-2)

Guidance literature:

1-Chlor-2-<4-brom-phenylmercapto>-aethan, Δ m. 30percent H2O2 in Essigsaeure;

upstream raw materials:

4-bromo-benzenesulfinic acid

2-chloro-ethanol

ethene

4-bromobenzenesulfonyl chloride

Downstream raw materials:

2-(4-bromophenyl)sulfonyl-N,N-dimethyl-ethanamine

2-(4-bromophenyl)sulfonyl-N,N-dimethyl-propan-1-amine

3-amino-6-(4-((1-(dimethylamino)propan-2-yl)sulfonyl)-phenyl)-N-phenylpyrazine-2-carboxamide

4-[2-(4-bromo-benzenesulfonyl)-ethyl]-morpholine