2-(3,5-dimethoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

• Chemical Name: 2-(3,5-dimethoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS No.: 1345024-09-0
• Molecular Formula: C₁₅H₂₃BO₄
• Molecular Weight: 278.156
• Mol file: 1345024-09-0.mol

Synonyms:2-(3,5-dimethoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of 2-(3,5-dimethoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3,5-dimethoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 1 articles about 2-(3,5-dimethoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2,6-dimethoxytoluene (5673-07-4) + bis(pinacol)diborane (73183-34-3) → 2-(3,5-dimethoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1345024-09-0)

Guidance literature:

bis(pinacol)diborane; With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine; In octane; at 20 ℃; for 0.25h;

2,6-dimethoxytoluene; In octane; at 125 ℃; for 72h;

DOI:10.1055/s-0030-1260166

Reference yield: 91.0%

(Z)-1-propenyl bromide (590-13-6) + 2-(3,5-dimethoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1345024-09-0) → 1,3-dimethoxy-2-methyl-5-[(Z)-prop-1-enyl]benzene (1345024-11-4)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; water; toluene; at 45 ℃; for 16h; Inert atmosphere;

DOI:10.1055/s-0030-1260166

Reference yield:

trans-2-propenyl bromide (590-15-8) + 2-(3,5-dimethoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1345024-09-0) → 1,3-dimethoxy-2-methyl-5-[(E)-prop-1-enyl]benzene (1345024-13-6) + 1,3-dimethoxy-2-methyl-5-(prop-1-en-2-yl)benzene (1345024-15-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; water; toluene; at 45 ℃; for 16h; Inert atmosphere;

DOI:10.1055/s-0030-1260166

upstream raw materials:

2,6-dimethoxytoluene

bis(pinacol)diborane

Downstream raw materials:

(2R,3S)-2-(3,5-dimethoxy-4-methylphenyl)-3-methyloxirane

(1S,2S)-1-(3,5-dimethoxy-4-methylphenyl)propane-1,2-diol

1,3-dimethoxy-2-methyl-5-[(Z)-prop-1-enyl]benzene

1,3-dimethoxy-2-methyl-5-[(E)-prop-1-enyl]benzene