(E)-5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxy-phenyl)-prop-2-enyl)-D-erythro-L-manno-nononic acid

Base Information

• Chemical Name: (E)-5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxy-phenyl)-prop-2-enyl)-D-erythro-L-manno-nononic acid
• CAS No.: 1314035-58-9
• Molecular Formula: C₂₁H₂₉NO₉
• Molecular Weight: 439.463
• Mol file: 1314035-58-9.mol

Synonyms:(E)-5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxy-phenyl)-prop-2-enyl)-D-erythro-L-manno-nononic acid

Chemical Property of (E)-5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxy-phenyl)-prop-2-enyl)-D-erythro-L-manno-nononic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxy-phenyl)-prop-2-enyl)-D-erythro-L-manno-nononic acid

There total 4 articles about (E)-5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxy-phenyl)-prop-2-enyl)-D-erythro-L-manno-nononic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(E)-methyl 5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxyphenyl)-prop-2-enyl)-D-erythro-L-manno-nononate (1314035-55-6) → (E)-5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxy-phenyl)-prop-2-enyl)-D-erythro-L-manno-nononic acid (1314035-58-9)

Guidance literature:

(E)-methyl 5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxyphenyl)-prop-2-enyl)-D-erythro-L-manno-nononate; With sodium hydroxide; In water; at 20 ℃;

In water; Acidic conditions;

DOI:10.1039/c0ob01176b

Reference yield:

4-Methoxystyrene (637-69-4,24936-44-5) → (E)-5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxy-phenyl)-prop-2-enyl)-D-erythro-L-manno-nononic acid (1314035-58-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 24 h / Reflux

2.1: methanol; sodium methylate / 20 °C

3.1: sodium hydroxide / water / 20 °C

3.2: Acidic conditions

With methanol; Hoveyda-Grubbs catalyst second generation; sodium methylate; sodium hydroxide; In dichloromethane; water;

DOI:10.1039/c0ob01176b

Reference yield:

(E)-methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxyphenyl)-prop-2-enyl)-D-erythro-L-manno-nononate (1314035-52-3) → (E)-5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxy-phenyl)-prop-2-enyl)-D-erythro-L-manno-nononic acid (1314035-58-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: methanol; sodium methylate / 20 °C

2.1: sodium hydroxide / water / 20 °C

2.2: Acidic conditions

With methanol; sodium methylate; sodium hydroxide; In water;

DOI:10.1039/c0ob01176b

upstream raw materials:

4-Methoxystyrene

(E)-methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxyphenyl)-prop-2-enyl)-D-erythro-L-manno-nononate

(E)-methyl 5-acetamido-2,6-anhydro-3,5-dideoxy-2-C-(3-(4-methoxyphenyl)-prop-2-enyl)-D-erythro-L-manno-nononate

(1S,2R)-1-((2R,3R,4S,6R)-3-acetamido-4-acetoxy-6-allyl-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyltriacetate