C₁₆H₁₄BrN

Base Information

• Chemical Name: C₁₆H₁₄BrN
• CAS No.: 1435467-17-6
• Molecular Formula: C₁₆H₁₄BrN
• Molecular Weight: 300.198
• Mol file: 1435467-17-6.mol

Synonyms:C₁₆H₁₄BrN

Chemical Property of C₁₆H₁₄BrN

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₁₆H₁₄BrN

There total 1 articles about C₁₆H₁₄BrN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

benzyl bromide (100-39-0) + 7-bromo-3-methyl-1H-indole (86915-22-2) → C16H14BrN (1435467-17-6)

Guidance literature:

7-bromo-3-methyl-1H-indole; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.25h; Inert atmosphere; Schlenk technique;

benzyl bromide; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 0.5h; Schlenk technique; Inert atmosphere;

DOI:10.1021/ja4042127

Reference yield: 91.0%

C16H14BrN (1435467-17-6) + dimethyl 2-(4-methoxyphenyl)cyclopropane-1,1-dicarboxylate (75073-97-1) → C30H30BrNO5 (1435466-87-7)

Guidance literature:

With C₅₁H₆₂N₂O₂; copper(II) bis(trifluoromethanesulfonate); In toluene; at 0 ℃; for 36h; enantioselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1021/ja4042127

upstream raw materials:

benzyl bromide

7-bromo-3-methyl-1H-indole

Downstream raw materials:

C₃₀H₃₀BrNO₅