86915-22-2

Basic information

• Product Name: 1H-Indole, 7-broMo-3-Methyl-
• Synonyms: 1H-Indole, 7-broMo-3-Methyl-;7-BroMo-3-Methylindole
• CAS NO: 86915-22-2
• Molecular Formula: C₉H₈BrN
• Molecular Weight: 210.07052
• Mol File: 86915-22-2.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 1H-Indole, 7-broMo-3-Methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 7-broMo-3-Methyl-(86915-22-2)
• EPA Substance Registry System: 1H-Indole, 7-broMo-3-Methyl-(86915-22-2)

Safety Data

• Hazardous Substances Data: 86915-22-2(Hazardous Substances Data)

Usage

General Description

1H-Indole, 7-bromo-3-methyl- is a chemical compound with the molecular formula C9H8BrN. It is a derivative of indole, which is a heterocyclic aromatic organic compound. The presence of a bromine atom at position 7 and a methyl group at position 3 gives this compound specific chemical and physical properties. 1H-Indole, 7-bromo-3-methyl- is used in various chemical synthesis processes and also has potential applications in pharmaceutical research and drug development. Studies have shown that this compound exhibits biological activities such as antimicrobial, anti-inflammatory, and anticancer properties, making it a potential candidate for further research and development.

Upstream product

• 67-56-1 methanol 
• 51417-51-7 7-bromo-1H-indole 
• 115666-21-2 7-bromo-1 H-indole-3-carbaldehyde 
• 16732-66-4 2-bromophenylhydrazine 
• 577-19-5 2-nitrophenyl bromide 
• 13154-14-8 1-propenylmagnesium bromide 
• 1730-25-2 allylmagnesium bromide 
• 242805-87-4 1-(2,2-diethylbutanoyl)-3-methylindole 
• 83-34-1 3-Methylindole 
• 1730-25-2 (E)-1-propenylmagnesium bromide 
• 242805-94-3 7-bromo-1-(2,2-diethylbutanoyl)-3-methylindole 
• 86915-15-3 3,7-Dibromo-3-methyl-1,3-dihydro-indol-2-one 

Downstream Products

• 83-34-1 3-Methylindole 
• 1257314-59-2 C₃₃H₂₇NP₂ 
• 1609470-53-2 C₁₇H₁₄BrF₂NO₂S 
• 1638769-31-9 C₁₇H₂₂N₂O₂ 
• 1435466-87-7 C₃₀H₃₀BrNO₅ 
• 1435467-17-6 C₁₆H₁₄BrN 

Relevant articles and documents

Ir(iii)-Catalysed electrooxidative intramolecular dehydrogenative C-H/N-H coupling for the synthesis of N-H indoles

Herein, an iridium(iii)-catalysed electrooxidative intramolecular dehydrogenative C-H/N-H coupling of unprotected 2-alkenyl anilines is described. The developed method allows the synthesis of a variety of 3-substituted N-H indole scaffolds under undivided electrolytic conditions. Mechanistic studies suggest that the reaction proceeds through the electro-oxidation induced reductive elimination pathway.

Organocatalytic Formal (3 + 2) Cycloaddition toward Chiral Pyrrolo[1,2- a]indoles via Dynamic Kinetic Resolution of Allene Intermediates

We report the chiral phosphoric acid catalyzed formal (3 + 2) cycloaddition of 3-substituted 1H-indoles and propargylic alcohols containing a functional directing group (p-NHAc or p-OH). This work represents a straightforward method to synthesize chiral pyrrolo[1,2-a]indole bearing a tetrasubstituted carbon stereocenter. The reaction proceeds smoothly with a wide array of substrate tolerance to deliver various chiral pyrrolo[1,2-a]indoles in up to 93percent yield and 98percent ee. The utility of this method is highlighted by the diverse transformations of the products into various indole derivatives.

Preparation method of 3-substituted oxidized indole and derivative

The invention belongs to the technical field of organic chemistry and pharmaceutical chemistry and particularly relates to a method of preparing 3-substituted oxidized indole and a derivative. In themethod, with a 3-substituted indole derivative as a raw material and one or more of a tetrabutyl ammonium halide compound/sodium chloride/sodium iodide/potassium iodide as additives, and one or more of dichloromethane/1,2-dichloroethane/tetrahydrofurane/methylbenzene/1,4-dioxane/ethyl acetate/methanol are added as solvents; then one or more of [bis(trifluoroacetoxyl)iodine]benzene/iodosobenzene diacetate are added as oxidants in order to carry out a reaction with reaction temperature being controlled, thus producing the 3-substituted oxidized indole derivative. The method has gentle reaction conditions, simple operations, short reaction time and high yield, and is free of a metal catalyst and is environment-friendly.