N-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-4-methoxy-N-methylbenzamide

Base Information

Chemical Name:N-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-4-methoxy-N-methylbenzamide
CAS No.:67579-70-8
Molecular Formula:C₁₇H₂₆N₂O₂
Molecular Weight:290.406
Hs Code.:
DSSTox Substance ID:DTXSID601345370,DTXSID001345453

Synonyms:DTXSID001345453;DTXSID601345370;N-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-4-methoxy-N-methylbenzamide;67579-70-8;rel-N-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-4-methoxy-N-methylbenzamide;2417942-52-8

Suppliers and Price of N-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-4-methoxy-N-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-4-methoxy-N-methylbenzamide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:290.199428076
Heavy Atom Count:21
Complexity:338

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)C1CCCCC1N(C)C(=O)C2=CC=C(C=C2)OC
Isomeric SMILES:CN(C)[C@@H]1CCCC[C@H]1N(C)C(=O)C2=CC=C(C=C2)OC

Technology Process of N-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-4-methoxy-N-methylbenzamide

There total 3 articles about N-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-4-methoxy-N-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67198-21-4
(±)-N,N-dimethyl-trans-1,2-diaminocyclohexane

: 67579-70-8
trans-N-<2-(dimethylamino)cyclohexyl>-p-methoxy-N-methylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / 17 h / Heating

2: 82 percent / LAH / diethyl ether / 17 h / Heating

3: triethylamine / diethyl ether / 17 h / Ambient temperature

With lithium aluminium tetrahydride; triethylamine; In diethyl ether;
DOI:10.1021/jm00150a017

Reference yield:

: 67198-27-0
trans-N-<2-(dimethylamino)cyclohexyl>formamide

: 67579-70-8
trans-N-<2-(dimethylamino)cyclohexyl>-p-methoxy-N-methylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / LAH / diethyl ether / 17 h / Heating

2: triethylamine / diethyl ether / 17 h / Ambient temperature

With lithium aluminium tetrahydride; triethylamine; In diethyl ether;
DOI:10.1021/jm00150a017