tert-butyl1-(3-((4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate

Base Information

Chemical Name:tert-butyl1-(3-((4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate
CAS No.:1354722-37-4
Molecular Formula:C₃₈H₄₁ClF₃N₅O₈
Molecular Weight:788.22
Hs Code.:

tert-butyl1-(3-((4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate

Synonyms:tert-butyl1-(3-((4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate

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Chemical Property of tert-butyl1-(3-((4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate

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Technology Process of tert-butyl1-(3-((4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate

There total 10 articles about tert-butyl1-(3-((4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1354722-17-0
2-amino-5-chloro-N-(1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)benzamide

: 1354722-36-3
tert-butyl 1-(3-(chlorocarbonyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate

: 1354722-37-4
tert-butyl1-(3-((4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; for 1h;

Reference yield:

: 401-81-0
m-trifluoromethylphenyl iodide

: 1354722-37-4
tert-butyl1-(3-((4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium carbonate; L-proline; copper(l) iodide / dimethyl sulfoxide / 85 °C

2.1: hydrogen / palladium on activated charcoal / methanol / 20 °C

3.1: pyridine / 1 h / 20 °C

4.1: zinc; acetic acid / 1 h / 70 °C

4.2: pH 8

5.1: N-ethyl-N,N-diisopropylamine / dichloromethane; tetrahydrofuran / 1 h

With pyridine; copper(l) iodide; hydrogen; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; L-proline; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide;

Reference yield:

: 1354722-12-5
3-nitro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole

: 1354722-37-4
tert-butyl1-(3-((4-chloro-2-((1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)carbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatetradecan-14-oate

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogen / palladium on activated charcoal / methanol / 20 °C

2.1: pyridine / 1 h / 20 °C

3.1: zinc; acetic acid / 1 h / 70 °C

3.2: pH 8

4.1: N-ethyl-N,N-diisopropylamine / dichloromethane; tetrahydrofuran / 1 h

With pyridine; hydrogen; acetic acid; N-ethyl-N,N-diisopropylamine; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;