(4S,2'E)-3-(6'-TBDPS-3'-methylhex-2'-enoyl)-4-phenyloxazolidin-2-one

Base Information

• Chemical Name: (4S,2'E)-3-(6'-TBDPS-3'-methylhex-2'-enoyl)-4-phenyloxazolidin-2-one
• CAS No.: 1092683-83-4
• Molecular Formula: C₃₂H₃₇NO₄Si
• Molecular Weight: 527.736
• Mol file: 1092683-83-4.mol

Synonyms:(4S,2'E)-3-(6'-TBDPS-3'-methylhex-2'-enoyl)-4-phenyloxazolidin-2-one

Chemical Property of (4S,2'E)-3-(6'-TBDPS-3'-methylhex-2'-enoyl)-4-phenyloxazolidin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4S,2'E)-3-(6'-TBDPS-3'-methylhex-2'-enoyl)-4-phenyloxazolidin-2-one

There total 1 articles about (4S,2'E)-3-(6'-TBDPS-3'-methylhex-2'-enoyl)-4-phenyloxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

tert-butyl{[(4E)-5-iodo-4-methylpent-4-en-1-yl]oxy}diphenylsilane (1044518-15-1) + carbon monoxide (201230-82-2) + (S)-4-phenyl-2-oxazolidinone (99395-88-7,7480-32-2) → (4S,2'E)-3-(6'-TBDPS-3'-methylhex-2'-enoyl)-4-phenyloxazolidin-2-one (1092683-83-4)

Guidance literature:

(S)-4-phenyl-2-oxazolidinone; With n-butyllithium; In tetrahydrofuran;

(E)-tert-butyl((5-iodo-4-methylpent-4-en-1-yl)oxy)diphenylsilane; carbon monoxide; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; under 3000.3 Torr;

DOI:10.1016/j.tetlet.2008.09.106

Reference yield: 79.0%

(4S,2'E)-3-(6'-TBDPS-3'-methylhex-2'-enoyl)-4-phenyloxazolidin-2-one (1092683-83-4) + tetravinyltin (IV) (1112-56-7) → C34H41NO4Si (1092683-84-5)

Guidance literature:

tetravinyltin (IV); With phenyllithium; In dibutyl ether; at 20 ℃; for 0.5h;

With copper(I) cyanide; In diethyl ether; dibutyl ether; at -78 - 0 ℃;

(4S,2'E)-3-(6'-TBDPS-3'-methylhex-2'-enoyl)-4-phenyloxazolidin-2-one; In diethyl ether; at -50 ℃; for 16h;

DOI:10.1016/j.tetlet.2008.09.106

Reference yield: 47.0%

(4S,2'E)-3-(6'-TBDPS-3'-methylhex-2'-enoyl)-4-phenyloxazolidin-2-one (1092683-83-4) + vinyl magnesium bromide (1826-67-1) → C34H41NO4Si (1092683-85-6) + C34H41NO4Si (1092683-84-5)

Guidance literature:

With copper(l) iodide; In tetrahydrofuran; at -78 ℃; for 12h;

DOI:10.1016/j.tetlet.2008.09.106

upstream raw materials:

tert-butyl{[(4E)-5-iodo-4-methylpent-4-en-1-yl]oxy}diphenylsilane

carbon monoxide

(S)-4-phenyl-2-oxazolidinone

Downstream raw materials:

C₃₄H₄₁NO₄Si

C₃₄H₄₁NO₄Si