(R)-3-phenylvaleryl chloride

Base Information

Chemical Name:(R)-3-phenylvaleryl chloride
CAS No.:159652-02-5
Molecular Formula:C₁₁H₁₃ClO
Molecular Weight:196.677
Hs Code.:

Synonyms:(R)-3-phenylvaleryl chloride

Suppliers and Price of (R)-3-phenylvaleryl chloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-3-phenylvaleryl chloride

Chemical Property:

Purity/Quality:

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Technology Process of (R)-3-phenylvaleryl chloride

There total 11 articles about (R)-3-phenylvaleryl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5669-17-0,16460-78-9,2845-27-4
(R) 3-phenylvaleric acid

: 159652-02-5
(R)-3-phenylvaleryl chloride

Guidance literature:: With thionyl chloride; In dichloromethane;
DOI:10.1021/ja00105a086

Reference yield:

: 100-58-3
phenylmagnesium bromide

: 159652-02-5
(R)-3-phenylvaleryl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: diethyl ether

2: Acidic conditions

3: oxalyl dichloride / dichloromethane / 2 h / Heating / reflux

With oxalyl dichloride; In diethyl ether; dichloromethane;

Reference yield:

: 104-54-1
3-Phenylpropenol

: 159652-02-5
(R)-3-phenylvaleryl chloride

Guidance literature:: Multi-step reaction with 6 steps

2: hydrogen / palladium on carbon

3: Alkaline conditions

4: diethyl chlorophosphate; triethylamine

5: phosphoric acid / 150 - 160 °C

6: oxalyl dichloride / dichloromethane / 2 h / Heating / reflux

With oxalyl dichloride; phosphoric acid; hydrogen; diethyl chlorophosphate; triethylamine; palladium on carbon; In dichloromethane; 1: Claisen Rearrangement;