2-<4-Trifluormethyl-phenylmercapto-methyl>-benzoesaeure-aethylester

Base Information

• Chemical Name: 2-<4-Trifluormethyl-phenylmercapto-methyl>-benzoesaeure-aethylester
• CAS No.: 852-23-3
• Molecular Formula: C₁₇H₁₅F₃O₂S
• Molecular Weight: 340.366
• Mol file: 852-23-3.mol

Synonyms:2-<4-Trifluormethyl-phenylmercapto-methyl>-benzoesaeure-aethylester

Chemical Property of 2-<4-Trifluormethyl-phenylmercapto-methyl>-benzoesaeure-aethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-<4-Trifluormethyl-phenylmercapto-methyl>-benzoesaeure-aethylester

There total 3 articles about 2-<4-Trifluormethyl-phenylmercapto-methyl>-benzoesaeure-aethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

o-(chloromethyl)benzoic acid ethyl ester (1531-78-8) + 4-trifluoromethylbenzenethiol (825-83-2) → 2-<4-Trifluormethyl-phenylmercapto-methyl>-benzoesaeure-aethylester (852-23-3)

Guidance literature:

With sodium hydroxide;

DOI:10.1002/hlca.19620450616

Reference yield:

ethyl 2-methylbenzoate (87-24-1) → 2-<4-Trifluormethyl-phenylmercapto-methyl>-benzoesaeure-aethylester (852-23-3)

Guidance literature:

Multi-step reaction with 2 steps

1: SO₂Cl₂, (PhCO)2O₂ / Irradiation

2: aq. NaOH

With sodium hydroxide; sulfuryl dichloride; dibenzoyl peroxide;

DOI:10.1002/hlca.19620450616

Reference yield:

→ 2-<4-Trifluormethyl-phenylmercapto-methyl>-benzoesaeure-aethylester (852-23-3)

Guidance literature:

Thiophenol IV (R= CF3), Ester III;

upstream raw materials:

o-(chloromethyl)benzoic acid ethyl ester

4-trifluoromethylbenzenethiol

ethyl 2-methylbenzoate

Downstream raw materials:

2-<(4-Trifluormethylmercapto-phenyl)-mercaptomethyl>-benzoesaeure