podocarpic acid benzyl ester

Base Information

• Chemical Name: podocarpic acid benzyl ester
• CAS No.: 783321-36-8
• Molecular Formula: C₂₄H₂₈O₃
• Molecular Weight: 364.485
• Mol file: 783321-36-8.mol

Synonyms:podocarpic acid benzyl ester

Chemical Property of podocarpic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of podocarpic acid benzyl ester

There total 2 articles about podocarpic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

podocarpic acid (5947-49-9) + benzyl bromide (100-39-0) → podocarpic acid benzyl ester (783321-36-8)

Guidance literature:

With potassium carbonate; In acetone; at 90 ℃; Microwave irradiation;

DOI:10.1021/ml500533x

Reference yield:

podocarpic acid (5947-49-9) + C13H22N2Si (783321-42-6) → podocarpic acid benzyl ester (783321-36-8)

Guidance literature:

With 2-chloropyridine; iodosylbenzene; hydrogen fluoride; In dichloromethane; ethyl acetate; at -78 - 23 ℃; for 11.5h;

DOI:10.1021/ja0459779

Reference yield: 91.0%

acrylic acid (79-10-7) + podocarpic acid benzyl ester (783321-36-8) → benzyl 12-O-acryloyl-podocarpate

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 90 ℃; for 0.25h; Microwave irradiation;

DOI:10.1021/ml500533x

upstream raw materials:

podocarpic acid

C₁₃H₂₂N₂Si

benzyl bromide

Refernces

• 1、 Furrow, Michael E.,Myers, Andrew G.. "A general procedure for the esterification of carboxylic acids with diazoalkanes generated in situ by the oxidation of N-tert- butyldimethylsilylhydrazones with (difluoroiodo)benzene". . p. 12222 - 12223. Retrieved 2007/10/03.