Diphenyl (alpha-anilino-2-pyridylmethyl)phosphonate

Base Information

Chemical Name:Diphenyl (alpha-anilino-2-pyridylmethyl)phosphonate
CAS No.:3360-70-1
Molecular Formula:C₂₄H₂₁N₂O₃P
Molecular Weight:416.416
Hs Code.:
European Community (EC) Number:653-018-1
Nikkaji Number:J954.459C

Synonyms:3360-70-1;Diphenyl ((phenylamino)(pyridin-2-yl)methyl)phosphonate;SCHEMBL5696985;DIPHENYL (ALPHA-ANILINO-2-PYRIDYLMETHYL)PHOSPHONATE;AKOS024429915;[(Phenylamino)(2-pyridinyl)methyl]phosphonic acid diphenyl ester

Suppliers and Price of Diphenyl (alpha-anilino-2-pyridylmethyl)phosphonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Diphenyl (alpha-anilino-2-pyridylmethyl)phosphonate

Chemical Property:

XLogP3:5.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:416.12897953
Heavy Atom Count:30
Complexity:519

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(C2=CC=CC=N2)P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4

Technology Process of Diphenyl (alpha-anilino-2-pyridylmethyl)phosphonate

There total 2 articles about Diphenyl (alpha-anilino-2-pyridylmethyl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.15%

: 1121-60-4
pyridine-2-carbaldehyde

: 4712-55-4
diphenyl hydrogen phosphite

: 62-53-3
aniline

: 3360-70-1
(anilino-pyridin-2-yl-methyl)-phosphonic acid diphenyl ester

Guidance literature:: In isopropyl alcohol; at 20 ℃; for 0.5h;

Reference yield:

: 3360-70-1
(anilino-pyridin-2-yl-methyl)-phosphonic acid diphenyl ester

Guidance literature:

Reference yield:

: 3360-70-1
(anilino-pyridin-2-yl-methyl)-phosphonic acid diphenyl ester

: 2-(3-Chloro-phenyl)-1-pyridin-2-yl-ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: anh. Cs₂CO₃ / tetrahydrofuran; propan-2-ol / 16 h / Ambient temperature

2: 3N HCl / H₂O; tetrahydrofuran; propan-2-ol / 2 h / Ambient temperature

With hydrogenchloride; caesium carbonate; In tetrahydrofuran; water; isopropyl alcohol;
DOI:10.1016/S0040-4039(98)00140-3