2-Amino-2-cyclopropyl-2-[3-(trifluoromethyl)phenyl]acetamide hydrochloride

Base Information

Chemical Name:2-Amino-2-cyclopropyl-2-[3-(trifluoromethyl)phenyl]acetamide hydrochloride
CAS No.:1245940-59-3
Molecular Formula:C₁₂H₁₃F₃N₂O*ClH
Molecular Weight:294.704
Hs Code.:

Synonyms:2-Amino-2-cyclopropyl-2-[3-(trifluoromethyl)phenyl]acetamide hydrochloride

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Chemical Property of 2-Amino-2-cyclopropyl-2-[3-(trifluoromethyl)phenyl]acetamide hydrochloride

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Technology Process of 2-Amino-2-cyclopropyl-2-[3-(trifluoromethyl)phenyl]acetamide hydrochloride

There total 1 articles about 2-Amino-2-cyclopropyl-2-[3-(trifluoromethyl)phenyl]acetamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 773837-37-9
sodium cyanide

: 38675-82-0
cyclopropyl(3-(trifluoromethyl)phenyl)methanone

: 1245940-59-3
2-Amino-2-cyclopropyl-2-[3-(trifluoromethyl)phenyl]acetamide hydrochloride

Guidance literature:: sodium cyanide; cyclopropyl(3-(trifluoromethyl)phenyl)methanone; With ammonia; water; In ethanol; for 17h;

With hydrogenchloride; In 1,4-dioxane; ethanol; water;

Reference yield: 25.0%

: 959140-61-5
{3-(4-chlorophenyl)-5-oxo-4-[(2,S)-3,3,3-trifluoro-2-hydroxypropyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}acetic acid

: 1245940-59-3
2-Amino-2-cyclopropyl-2-[3-(trifluoromethyl)phenyl]acetamide hydrochloride

: 1245940-91-3
2-[({3-(4-Chlorophenyl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}acetyl)amino]-2-cyclopropyl-2-[3-(trifluoromethyl)phenyl]acetamide

Guidance literature:: With N¹-((ethylimino)methylene)-N³,N³-dimethylpropane-1,3-diamine hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h;