38675-82-0

Usage

Uses

Used in Organic Synthesis:
CYCLOPROPYL 3-TRIFLUOROMETHYLPHENYL KETONE is used as a building block for the synthesis of various biologically active molecules, contributing to the development of new organic compounds with potential applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, CYCLOPROPYL 3-TRIFLUOROMETHYLPHENYL KETONE serves as a key intermediate in the synthesis of drug candidates, aiding in the discovery and development of novel therapeutic agents.
It is important to handle CYCLOPROPYL 3-TRIFLUOROMETHYLPHENYL KETONE with caution, as it may pose health and environmental hazards due to its reactivity and potential toxicity.

InChI:InChI=1/C11H9F3O/c12-11(13,14)9-3-1-2-8(6-9)10(15)7-4-5-7/h1-3,6-7H,4-5H2

Upstream product

• 401-78-5 3-bromo-1-trifluoromethylbenzene 
• 5500-21-0 cyclopropropanecarbonitrile 
• 2251-65-2 3-(Trifluoromethyl)benzoyl chloride 
• 23719-80-4 cyclopropylmagnesium bromide 
• 116332-62-8 N-methoxy-N-methyl-3-trifluoromethylbenzamide 
• 925430-09-7 tricyclopropylbismuthane 
• 201230-82-2 carbon monoxide 
• 401-81-0 m-trifluoromethylphenyl iodide 

Downstream Products

• 6552-47-2 (m-Trifluormethylphenyl)-cyclopropyl-carbinol 
• 1245940-59-3 2-Amino-2-cyclopropyl-2-[3-(trifluoromethyl)phenyl]acetamide hydrochloride 
• 1429308-62-2 9a-(3-(trifluoromethyl)phenyl)-7,8,9,9a-tetrahydrothieno[2,3-g]indolizin-5(4H)-one 

Relevant academic research and scientific papers

Palladium-Catalyzed Carbonylative Cross-Coupling Reaction between Aryl(Heteroaryl) Iodides and Tricyclopropylbismuth: Expedient Access to Aryl Cyclopropylketones

The carbonylative cross-coupling reaction between aryl and heteroaryl iodides and tricyclopropylbismuth is reported. The reaction is catalyzed by (SIPr)Pd(allyl)Cl, a NHC-palladium(II) catalyst, operates under 1 atm of carbon monoxide and tolerates a wide range of functional groups. The use of lithium chloride was found to provide higher yields of the desired aryl cyclopropylketones. The conditions were also applied to the carbonylative cross-coupling of an iodoalkene to afford the corresponding alkenyl cyclopropylketone.

TETRAZOLINONE COMPOUND AND USE THEREOF

The compound represented by formula (1): wherein R4 and R5 each represents a hydrogen atom, a halogen atom, or a C1-C3 alkyl group; R6 represents a C1-C4 alkyl group, a C3-C6 cycloalkyl group, or the like; R7, R8, and R9 each represents a hydrogen atom, a halogen atom, or the like; R10 represents a C1-C3 alkyl group, or the like; R13 represents a C1-C3 alkyl group, or the like; and Q represents a phenyl group, or the like; has an excellent control effect on pests.

A cascade approach to fused indolizinones through Lewis acid-copper(i) relay catalysis

A relay catalytic cascade process involving Lewis acid triggered ring-opening of cyclopropyl ketones with nitriles, the copper(i)-catalyzed Ritter process, and acid-promoted N-acyliminium ion cyclization is described, which efficiently provides thieno-, furano-, and benzo-indolizinones in moderate to good yields. The Royal Society of Chemistry 2013.