NSC42124

Base Information

• Chemical Name: NSC42124
• CAS No.: 6633-62-1
• Molecular Formula: C16H10 Cl N O2
• Molecular Weight: 283.714
• Hs Code.: 2933499090
• Mol file: 6633-62-1.mol

Synonyms:2-Phenyl-6-chloro-4-quinolinecarboxylicacid; 6-Chloro-2-phenylcinchoninic acid; 6-Chloro-2-phenylquinoline-4-carboxylicacid; NSC 42124

Chemical Property of NSC42124

Chemical Property:

• Vapor Pressure: 3.25E-10mmHg at 25°C
• Boiling Point: 484.9°C at 760 mmHg
• Flash Point: 247°C
• PSA: 50.19000
• Density: 1.373g/cm³
• LogP: 4.25340

Purity/Quality:

98%min ^*data from raw suppliers

6-Chloro-2-phenylquinoline-4-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NSC42124

There total 4 articles about NSC42124 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

benzaldehyde (100-52-7) + 4-chloro-aniline (106-47-8) + 2-oxo-propionic acid (127-17-3) → 6-chloro-2-phenylquinoline-4-carboxylic acid (6633-62-1)

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; for 0.05h; Microwave irradiation; Green chemistry;

DOI:10.1002/jhet.3848

Reference yield: 54.0%

5-chloroindole 2,3-dione (17630-76-1) + acetophenone (98-86-2) → 6-chloro-2-phenylquinoline-4-carboxylic acid (6633-62-1)

Guidance literature:

With potassium hydroxide; In ethanol; water; at 80 - 90 ℃;

DOI:10.3987/COM-14-12939

Reference yield:

4-chloro-aniline (106-47-8) → 6-chloro-2-phenylquinoline-4-carboxylic acid (6633-62-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium sulfate; hydrogenchloride; hydroxylamine hydrochloride / water / 2.5 h / 85 °C

2: sulfuric acid / 60 - 90 °C

3: potassium hydroxide / ethanol / 72.5 h / Reflux

With hydrogenchloride; sulfuric acid; hydroxylamine hydrochloride; sodium sulfate; potassium hydroxide; In ethanol; water;

DOI:10.2174/1570180811310050009

upstream raw materials:

5-chloroindole 2,3-dione

acetophenone

benzaldehyde

4-chloro-aniline

Downstream raw materials:

6-chloro-2-phenyl-quinoline-4-carbonyl chloride

C₂₂H₁₄Cl₂N₂O

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 6633-62-1 NSC42124

Send

Send

Metric Ton KG G Pound L ML

Send

Send