(±)-dimethyl-[α-(4-methoxyphenyl) (napthalen-1-ylamino)methyl] phosphonate

Base Information

• Chemical Name: (±)-dimethyl-[α-(4-methoxyphenyl) (napthalen-1-ylamino)methyl] phosphonate
• CAS No.: 32394-86-8
• Molecular Formula: C₂₀H₂₂NO₄P
• Molecular Weight: 371.373
• Mol file: 32394-86-8.mol

Synonyms:(±)-dimethyl-[α-(4-methoxyphenyl) (napthalen-1-ylamino)methyl] phosphonate

Chemical Property of (±)-dimethyl-[α-(4-methoxyphenyl) (napthalen-1-ylamino)methyl] phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (±)-dimethyl-[α-(4-methoxyphenyl) (napthalen-1-ylamino)methyl] phosphonate

There total 2 articles about (±)-dimethyl-[α-(4-methoxyphenyl) (napthalen-1-ylamino)methyl] phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-amino-naphthalene (134-32-7) + 4-methoxy-benzaldehyde (123-11-5) + Dimethyl phosphite (868-85-9) → (±)-dimethyl-[α-(4-methoxyphenyl) (napthalen-1-ylamino)methyl] phosphonate (32394-86-8)

Guidance literature:

With silica supported 20percent dodecatungstophosphoric acid; In acetonitrile; at 20 ℃; for 1h; Green chemistry;

DOI:10.1039/c3ra45853a

Reference yield:

→ (±)-dimethyl-[α-(4-methoxyphenyl) (napthalen-1-ylamino)methyl] phosphonate (32394-86-8)

Guidance literature:

entspr. Azomethin, Dimethylhydrogenphosphit;

Reference yield: 49.0%

(±)-dimethyl-[α-(4-methoxyphenyl) (napthalen-1-ylamino)methyl] phosphonate (32394-86-8) → (±)-α-(4-methoxyphenyl)(napthalen-1-ylamino)methyl phosphonic acid

Guidance literature:

With trimethylsilyl bromide; In dichloromethane; N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

DOI:10.1016/j.ejmech.2018.08.089

upstream raw materials:

1-amino-naphthalene

4-methoxy-benzaldehyde

Dimethyl phosphite