1-ethyl-1,2-dihydro-2-phenyl-1,2-azaborine

Base Information

• Chemical Name: 1-ethyl-1,2-dihydro-2-phenyl-1,2-azaborine
• CAS No.: 287735-81-3
• Molecular Formula: C₁₂H₁₄BN
• Molecular Weight: 183.061
• Mol file: 287735-81-3.mol

Synonyms:1-ethyl-1,2-dihydro-2-phenyl-1,2-azaborine

Chemical Property of 1-ethyl-1,2-dihydro-2-phenyl-1,2-azaborine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1-ethyl-1,2-dihydro-2-phenyl-1,2-azaborine

There total 7 articles about 1-ethyl-1,2-dihydro-2-phenyl-1,2-azaborine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-chloro-1-ethyl-1,2-azaborine (959928-06-4) + trimethyl(phenyl)stannane (934-56-5) → 1-ethyl-1,2-dihydro-2-phenyl-1,2-azaborine (287735-81-3)

Guidance literature:

With chlorobis(ethylene)rhodium(I) dimer; 2,2'-bis(diphenylphosphino)biphenyl; In tetrahydrofuran; at 100 ℃; for 24h; Reagent/catalyst;

DOI:10.1002/anie.201304443

Reference yield: 76.0%

2-chloro-1-ethyl-1,2-azaborine (959928-06-4) + phenylmagnesium bromide → 1-ethyl-1,2-dihydro-2-phenyl-1,2-azaborine (287735-81-3)

Guidance literature:

In diethyl ether; at -78 - 20 ℃;

DOI:10.1021/ol702383u

Reference yield: 64.0%

dichloromethane (75-09-2) + 1-ethyl-2,3-dihydro-2-phenyl-1H-1,2-azaborol-3-yllithium → 1-ethyl-1,2-dihydro-2-phenyl-1,2-azaborine (287735-81-3)

Guidance literature:

With lithium diisopropyl amide; In diethyl ether; dichloromethane; under N2; Li salt was mixt. with CH2Cl2 and cooled to -78°C, a soln. of lithium diisopropylamide in (CH3CH2)2O was added, the mixt. was stirred at -78°C for 1 h, warmed to 25°C, the mixt. was stirred at 25°C for 10 h; the solvent was removed, the residue was extd. with pentane, filtered, pentane was removed, the residue was chromd. on silica gel with hexane; elem. anal.;

DOI:10.1021/om0106635

upstream raw materials:

1-ethyl-3,6-dihydro-2-phenyl-1,2-azaborine

2-chloro-1-ethyl-1,2-azaborine

N-allyl-N-ethylaminoallylboron chloride

N-allyl-N-ethylaminoallylphenylborane