Preclamol

Base Information

Chemical Name:Preclamol
CAS No.:85966-89-8
Molecular Formula:C14H21 N O
Molecular Weight:219.327
Hs Code.:
UNII:9V2O6CRQ6Z
DSSTox Substance ID:DTXSID7048453
Nikkaji Number:J275.058I
Wikipedia:3-PPP
Wikidata:Q27273260
NCI Thesaurus Code:C82251
Pharos Ligand ID:X7A67U8FV4BW
ChEMBL ID:CHEMBL7549

Synonyms:3-(3-hydroxyphenyl)-N-n-propylpiperidine;3-PPP;n-N-propyl-3(N-hydroxyphenyl)piperidine;n-N-propyl-3-(3-hydroxyphenyl)piperidine;n-N-propyl-3-(3-hydroxyphenyl)piperidine, (+-)-isomer;n-N-propyl-3-(3-hydroxyphenyl)piperidine, R-(+)-isomer;n-N-propyl-3-(3-hydroxyphenyl)piperidine, S-(-)-isomer;preclamol

Suppliers and Price of Preclamol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Preclamol

Chemical Property:

Vapor Pressure:3.85E-05mmHg at 25°C
Boiling Point:342.2°C at 760 mmHg
Flash Point:158°C
Density:1.023g/cm³
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:219.162314293
Heavy Atom Count:16
Complexity:207

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN1CCCC(C1)C2=CC(=CC=C2)O
Isomeric SMILES:CCCN1CCC[C@H](C1)C2=CC(=CC=C2)O

Technology Process of Preclamol

There total 38 articles about Preclamol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 89874-51-1
(+)-(S)-3-(3-methoxyphenyl)-1-propylpiperidine

: 85966-89-8
preclamol

Guidance literature:: With hydrogen bromide; In water; for 0.5h; Heating / reflux;

Reference yield: 84.0%

: 107-10-8,42939-71-9
propylamine

: (S)-2-(3-methoxyphenyl)pentane-1,5-diol

: 85966-89-8
preclamol

Guidance literature:: (S)-2-(3-methoxyphenyl)pentane-1,5-diol; With methanesulfonyl chloride; triethylamine; In dichloromethane; at -20 ℃; for 2h;

propylamine; at 20 ℃; for 15h;

With hydrogen bromide; at 120 ℃; for 2h; enantioselective reaction;
DOI:10.1039/c6sc04609f

Reference yield:

: 89874-51-1
(+)-(S)-3-(3-methoxyphenyl)-1-propylpiperidine

: 85966-89-8
preclamol

: 85976-54-1
(+)-preclamol

Guidance literature:: With hydrogen bromide; at 20 - 120 ℃; for 2h; Overall yield = 0.133 g; enantioselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1055/s-0037-1611759