2-Methylbenzyltrimethylsilane

Base Information

• Chemical Name: 2-Methylbenzyltrimethylsilane
• CAS No.: 4225-37-0
• Molecular Formula: C₁₁H₁₈Si
• Molecular Weight: 178.349
• DSSTox Substance ID: DTXSID901266232
• Nikkaji Number: J1.428.205J
• Mol file: 4225-37-0.mol

Synonyms:1-methyl-2-trimethylsilanylmethyl-benzene;2-Methylbenzyltrimethylsilane;DTXSID901266232;AKOS004907964;4225-37-0;1-Methyl-2-[(trimethylsilyl)methyl]benzene

Chemical Property of 2-Methylbenzyltrimethylsilane

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 178.117777109
• Heavy Atom Count: 12
• Complexity: 134

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=CC=C1C[Si](C)(C)C

Technology Process of 2-Methylbenzyltrimethylsilane

There total 9 articles about 2-Methylbenzyltrimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

bis(tetrahydrofuran)tris(trimethylsilylmethyl)yttrium(III) + ortho-methylphenyl iodide (615-37-2) → o-<(trimethylsilyl)methyl>toluene (4225-37-0)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos; In toluene; at 20 ℃; for 1h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c6cc01312k

Reference yield: 63.0%

1,1,1,2,2,2-hexamethyldisilane (1450-14-2) + 2-tolylmethylnitrile (22364-68-7) → C15H27NSi2 + o-<(trimethylsilyl)methyl>toluene (4225-37-0)

Guidance literature:

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; In ethyl-cyclohexane; at 160 ℃; for 15h; Inert atmosphere;

DOI:10.1021/ja804992n

Reference yield:

chloro-trimethyl-silane (75-77-4) → o-<(trimethylsilyl)methyl>toluene (4225-37-0)

Guidance literature:

In tetrahydrofuran; at 65 ℃; for 0.166667h;

DOI:10.1002/ejoc.201901063

upstream raw materials:

chloro-trimethyl-silane

o-xylene

1-chloromethyl-2-methylbenzene

α-chloro-o-<(trimethylsilyl)methyl>acetophenone

Downstream raw materials:

o-<α-(bromo)-α-(trimethylsilyl)-methyl>benzyl bromide

allyl o-tolyl ether

1-(Bis-trimethylsilanyl-methyl)-2-methyl-benzene

1-(Bis-trimethylsilanyl-methyl)-2-trimethylsilanylmethyl-benzene