4-(3,3-difluorocyclobutoxy)-5-methanesulfonyl-2-methylbenzoic acid methyl ester

Base Information

Chemical Name:4-(3,3-difluorocyclobutoxy)-5-methanesulfonyl-2-methylbenzoic acid methyl ester
CAS No.:637031-90-4
Molecular Formula:C₁₄H₁₆F₂O₅S
Molecular Weight:334.341
Hs Code.:

Synonyms:4-(3,3-difluorocyclobutoxy)-5-methanesulfonyl-2-methylbenzoic acid methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(3,3-difluorocyclobutoxy)-5-methanesulfonyl-2-methylbenzoic acid methyl ester

Chemical Property:

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Technology Process of 4-(3,3-difluorocyclobutoxy)-5-methanesulfonyl-2-methylbenzoic acid methyl ester

There total 1 articles about 4-(3,3-difluorocyclobutoxy)-5-methanesulfonyl-2-methylbenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 637031-88-0
3,3-difluorocyclobutan-1-ol

: 190367-50-1
4-fluoro-5-methanesulfonyl-2-methyl-benzoic acid methyl ester

: 637031-90-4
4-(3,3-difluorocyclobutoxy)-5-methanesulfonyl-2-methylbenzoic acid methyl ester

Guidance literature:: With caesium carbonate; In 1-methyl-pyrrolidin-2-one; at 60 ℃; for 4h;

Reference yield:

: 637031-90-4
4-(3,3-difluorocyclobutoxy)-5-methanesulfonyl-2-methylbenzoic acid methyl ester

: 50-01-1
guanidine hydrochloride

: N-[4-(3,3-difluorocyclobutoxy)-5-methanesulfonyl-2-methylbenzoyl]-guanidine

Guidance literature:: guanidine hydrochloride; With potassium tert-butylate; In DMF (N,N-dimethyl-formamide);

4-(3,3-difluorocyclobutoxy)-5-methanesulfonyl-2-methylbenzoic acid methyl ester; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 24h;