2,3-Dichloropropanal

Base Information

• Chemical Name: 2,3-Dichloropropanal
• CAS No.: 10140-89-3
• Molecular Formula: C3H4 Cl2 O
• Molecular Weight: 126.97
• Hs Code.: 2913000090
• European Community (EC) Number: 233-399-7
• UNII: QX2J64S05F
• DSSTox Substance ID: DTXSID80906137
• Nikkaji Number: J24.190C
• Wikidata: Q27287537
• Mol file: 10140-89-3.mol

Synonyms:2,3-Dichloropropanal;2,3-Dichloropropionaldehyde;10140-89-3;Propanal, 2,3-dichloro-;Propionaldehyde, 2,3-dichloro-;1,2-Dichloro-3-propional;BRN 1742015;alpha,beta-Dichloropropionaldehyde;EINECS 233-399-7;23-Dichloropropionaldehyde;UNII-QX2J64S05F;QX2J64S05F;4-01-00-03174 (Beilstein Handbook Reference);SCHEMBL901509;DTXSID80906137;AKOS006278722;LS-123973;.ALPHA.,.BETA.-DICHLOROPROPIONALDEHYDE;Q27287537

Chemical Property of 2,3-Dichloropropanal

Chemical Property:

• Vapor Pressure: 3.26mmHg at 25°C
• Refractive Index: 1.4762 (estimate)
• Boiling Point: 153.9°Cat760mmHg
• Flash Point: 54.7°C
• PSA: 17.07000
• Density: 1.288g/cm³
• LogP: 1.03150
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 125.9639201
• Heavy Atom Count: 6
• Complexity: 46.1

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,3-DICHLOROPROPIONALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C=O)Cl)Cl

Technology Process of 2,3-Dichloropropanal

There total 12 articles about 2,3-Dichloropropanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

acrolein (107-02-8,25068-14-8) → 2,3-dichloropropanal (10140-89-3)

Guidance literature:

With hydrogenchloride; chlorine; In tetrachloromethane; at 15 - 20 ℃;

Reference yield: 52.0%

trans-1,3-dichloropropene epoxide (66826-73-1) → 2,3-dichloropropanal (10140-89-3) + 2,5-Dihydroxy-3,6-bis(chloromethyl)-1,4-dioxane (76429-86-2)

Guidance literature:

In tetrahydrofuran; water; at 20 ℃; for 168h; Title compound not separated from byproducts; pH 7.4;

DOI:10.1021/jo00320a029

Reference yield: 52.0%

cis-1,3-dichloropropene epoxide (66826-72-0) → 2,3-dichloropropanal (10140-89-3) + 2,5-Dihydroxy-3,6-bis(chloromethyl)-1,4-dioxane (76429-86-2)

Guidance literature:

In tetrahydrofuran; water; at 20 ℃; for 168h; Title compound not separated from byproducts; pH 7.4;

DOI:10.1021/jo00320a029

upstream raw materials:

acrolein

trans-1,3-dichloropropene epoxide

cis-1,3-dichloropropene epoxide

tetrachloromethane

Downstream raw materials:

2,3-Dichloro-1-propanol

2,2,3-trichloro-propionaldehyde

5-Chloro-8-hydroxyquinoline

Refernces

• 1、 Hatano, Manabu,Mizuno, Tomokazu,Izumiseki, Atsuto,Usami, Ryota,Asai, Takafumi,Akakura, Matsujiro,Ishihara, Kazuaki. "Enantioselective diels-alder reactions with anomalous endo/exo selectivities using conformationally flexible chiral supramolecular catalysts". supporting information; experimental part. p. 12189 - 12192. Retrieved 2012/02/01.
• 2、 -. "Process for making 2,3-dihalopropanols". . . Retrieved 2008/06/13.