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Basic Information
CAS No.: 10140-89-3
Name: 2,3-Dichloropropionaldehyde
Molecular Structure:
Molecular Structure of 10140-89-3 (2,3-Dichloropropionaldehyde)
Formula: C3H4 Cl2 O
Molecular Weight: 126.97
Synonyms: Propionaldehyde,2,3-dichloro- (6CI,7CI,8CI); 2,3-Dichloropropanal; 2,3-Dichloropropionaldehyde;a,b-Dichloropropionaldehyde
Density: 1.288g/cm3
Boiling Point: 153.9°Cat760mmHg
Flash Point: 54.7°C
Safety: Poison by ingestion and skin contact. Mildly toxic by inhalation. A severe skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl. See also ALDEHYDES and CHLORIDES.
PSA: 17.07000
LogP: 1.03150
Synthetic route
107-02-8

acrolein

10140-89-3

2,3-dichloropropanal

Conditions
ConditionsYield
With hydrogenchloride; chlorine In tetrachloromethane at 15 - 20℃;80%
With chlorine at -10 - 0℃; for 1h;71%
With tetrachloromethane; chlorine
66826-73-1

trans-1,3-dichloropropene epoxide

A

10140-89-3

2,3-dichloropropanal

B

76429-86-2

2,5-Dihydroxy-3,6-bis(chloromethyl)-1,4-dioxane

Conditions
ConditionsYield
In tetrahydrofuran; water at 20℃; for 168h; pH 7.4; Title compound not separated from byproducts;A 52%
B 20%
In tetrahydrofuran; water at 20℃; for 168h; pH 7.4;A 52%
B 20%
66826-72-0

cis-1,3-dichloropropene epoxide

A

10140-89-3

2,3-dichloropropanal

B

76429-86-2

2,5-Dihydroxy-3,6-bis(chloromethyl)-1,4-dioxane

Conditions
ConditionsYield
In tetrahydrofuran; water at 20℃; for 168h; pH 7.4; Title compound not separated from byproducts;A 52%
B 20%
In tetrahydrofuran; water at 20℃; for 168h; pH 7.4;A 52%
B 20%

4,5-dichloro-pent-2-enoic acid

A

10140-89-3

2,3-dichloropropanal

B

144-62-7

oxalic acid

Conditions
ConditionsYield
bei Ozonabbau;
66826-73-1

trans-1,3-dichloropropene epoxide

A

10140-89-3

2,3-dichloropropanal

B

84709-24-0

2-Hydroxy-3-chloropropanal

C

76429-86-2

2,5-Dihydroxy-3,6-bis(chloromethyl)-1,4-dioxane

Conditions
ConditionsYield
With water In tetrahydrofuran at 20℃; for 168h; pH 7.4; Yields of byproduct given. Title compound not separated from byproducts;
With water In tetrahydrofuran at 20℃; for 168h; pH 7.4;
66826-72-0

cis-1,3-dichloropropene epoxide

A

10140-89-3

2,3-dichloropropanal

B

84709-24-0

2-Hydroxy-3-chloropropanal

C

76429-86-2

2,5-Dihydroxy-3,6-bis(chloromethyl)-1,4-dioxane

Conditions
ConditionsYield
With water In tetrahydrofuran at 20℃; for 168h; pH 7.4; Yields of byproduct given. Title compound not separated from byproducts;
With water In tetrahydrofuran at 20℃; for 168h; pH 7.4;

cis-1,3-Dichloropropene epoxide

A

683-51-2

2-chloro-2-propenal

B

10140-89-3

2,3-dichloropropanal

Conditions
ConditionsYield
With dimethylsulfoxide-d6 at 22℃; Kinetics; Rearrangement;

trans-1,3-Dichloropropene epoxide

A

683-51-2

2-chloro-2-propenal

B

10140-89-3

2,3-dichloropropanal

Conditions
ConditionsYield
With dimethylsulfoxide-d6 at 22℃; Kinetics; Rearrangement;
56-23-5

tetrachloromethane

7782-50-5

chlorine

107-02-8

acrolein

10140-89-3

2,3-dichloropropanal

310447-99-5, 310448-01-2

3,4-dichlorobut-1-ene

A

50-00-0

formaldehyd

B

10140-89-3

2,3-dichloropropanal

Conditions
ConditionsYield
at 0℃; Erwaermen des enthaltenen Ozonids mit Wasser;
Downstream Products
130-16-5
616-23-9
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Chemistry

Empirical Formula of 2,3-Dichloropropionaldehyde (CAS NO.10140-89-3): C3H4Cl2O
Molecular Weight: 126.9693 g/mol
EINECS: 233-399-7 
Index of Refraction: 1.436
Density: 1.288 g/cm3
Flash Point: 54.7 °C
Enthalpy of Vaporization: 39.07 kJ/mol
Boiling Point: 153.9 °C at 760 mmHg
Vapour Pressure: 3.26 mmHg at 25 °C
Structure of 2,3-Dichloropropionaldehyde (CAS NO.10140-89-3):
                
IUPAC Name of 2,3-Dichloropropionaldehyde (CAS NO.10140-89-3): 2,3-Dichloropropanal

Toxicity Data With Reference

1.    

skn-rbt 10 mg/24H open SEV

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.
2.    

skn-rbt 500 mg MOD

    SCCUR*    Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583)
3.    

eye-rbt 50 µg open SEV

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.
4.    

mmo-sat 1 nmol/plate

    MUREAV    Mutation Research. 78 (1980),113.
5.    

orl-rat LD50:160 mg/kg

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.
6.    

ihl-rat LCLo:2500 ppb/4H

    SCCUR*    Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583)
7.    

orl-mus LD50:250 mg/kg

    SCCUR*    Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583)
8.    

ihl-mus LCLo:9300 ppm/15M

    SCCUR*    Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583)
9.    

skn-rbt LD50:78 mg/kg

    AMIHBC    AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.

Safety Profile

Poison by ingestion and skin contact. Mildly toxic by inhalation. A severe skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl. See also ALDEHYDES and CHLORIDES.

Specification

 2,3-Dichloropropionaldehyde ,its cas register number is 10140-89-3. It also can be called 1,2-Dichloro-3-propional ;and Propionaldehyde, 2,3-dichloro- .