Technology Process of tert-butyl {5-[(4-methoxybenzyl)oxy]-2-nitrophenyl}methylcarbamate
There total 1 articles about tert-butyl {5-[(4-methoxybenzyl)oxy]-2-nitrophenyl}methylcarbamate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 20 - 80 ℃;
for 4h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: iron; ammonium chloride / water; ethanol / 5 h / Reflux
2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 3 h / 20 °C / Inert atmosphere
3: hydrogenchloride / 1,4-dioxane / 2 h / 60 °C
4: copper(l) iodide; 1,10-Phenanthroline; caesium carbonate / N,N-dimethyl-formamide / 2 h / 80 °C / Inert atmosphere
With
hydrogenchloride; copper(l) iodide; 1,10-Phenanthroline; iron; ammonium chloride; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
1,4-dioxane; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2018.09.005
- Guidance literature:
-
Multi-step reaction with 4 steps
1: iron; ammonium chloride / water; ethanol / 5 h / Reflux
2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 3 h / 20 °C / Inert atmosphere
3: hydrogenchloride / 1,4-dioxane / 2 h / 60 °C
4: copper(l) iodide; 1,10-Phenanthroline; caesium carbonate / N,N-dimethyl-formamide / 2 h / 80 °C / Inert atmosphere
With
hydrogenchloride; copper(l) iodide; 1,10-Phenanthroline; iron; ammonium chloride; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
1,4-dioxane; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2018.09.005