1-iodo-2-(2-iodophenyl)naphthalene

Base Information

• Chemical Name: 1-iodo-2-(2-iodophenyl)naphthalene
• CAS No.: 69452-58-0
• Molecular Formula: C₁₆H₁₀I₂
• Molecular Weight: 456.064
• Mol file: 69452-58-0.mol

Synonyms:1-iodo-2-(2-iodophenyl)naphthalene

Chemical Property of 1-iodo-2-(2-iodophenyl)naphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-iodo-2-(2-iodophenyl)naphthalene

There total 9 articles about 1-iodo-2-(2-iodophenyl)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

benzo[b]naphtho[2,1-d]iodol-11-ium trifluoromethanesulfonate (1469876-15-0) → 1-iodo-2-(2-iodophenyl)naphthalene (69452-58-0)

Guidance literature:

With copper(l) iodide; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane; tetra-(n-butyl)ammonium iodide; In 1,4-dioxane; at 20 ℃; for 24h; regioselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1002/anie.201503134

Reference yield:

2-(2-iodophenyl)naphthalene (97295-35-7) → 1-iodo-2-(2-iodophenyl)naphthalene (69452-58-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 20 °C

2: copper(l) iodide; tetra-(n-butyl)ammonium iodide; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane / 1,4-dioxane / 24 h / 20 °C / Schlenk technique; Inert atmosphere

With copper(l) iodide; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane; tetra-(n-butyl)ammonium iodide; 3-chloro-benzenecarboperoxoic acid; In 1,4-dioxane; dichloromethane;

DOI:10.1002/anie.201503134

Reference yield:

2-(2-naphthyl)aniline (71221-26-6) → 1-iodo-2-(2-iodophenyl)naphthalene (69452-58-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogenchloride; sodium nitrite / water; tetrahydrofuran / 0.33 h / 0 °C

1.2: 1.17 h / 0 - 20 °C

2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 20 °C

3.1: copper(l) iodide; tetra-(n-butyl)ammonium iodide; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane / 1,4-dioxane / 24 h / 20 °C / Schlenk technique; Inert atmosphere

With hydrogenchloride; copper(l) iodide; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane; tetra-(n-butyl)ammonium iodide; 3-chloro-benzenecarboperoxoic acid; sodium nitrite; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water;

DOI:10.1002/anie.201503134

upstream raw materials:

2-phenylnaphthalene

1-bromo-2-phenylnaphthalene

1-iodo-2-phenylnaphthalene

diacetoxy-(2-phenyl-naphthalen-1-yl)-λ³-iodane

Downstream raw materials:

3,7-dimethyl-5-phenyl-5H-5λ⁵-spiro[benzo[b]phosphindole-5,11'-dibenzo[b,g]phosphindole]

11-phenyl-11H-dibenzo[b,h]phosphindole