Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine

Base Information

• Chemical Name: Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine
• CAS No.: 246509-62-6
• Molecular Formula: C₁₁H₁₃N
• Molecular Weight: 159.231
• Mol file: 246509-62-6.mol

Synonyms:Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine

Chemical Property of Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine

There total 1 articles about Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-amino-2-propene (107-11-9,30551-89-4) + m-tolyl aldehyde (620-23-5) → Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine (246509-62-6)

Guidance literature:

With magnesium sulfate; In dichloromethane; at 20 ℃; for 20h;

DOI:10.1002/adsc.200600370

Reference yield: 98.0%

hydrogen cyanide (74-90-8) + trifluoroacetic anhydride (407-25-0) + Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine (246509-62-6) → (S)-N-trifluoroacetyl-α-allylamino-3-methyl-phenyl-acetonitrile

Guidance literature:

hydrogen cyanide; Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine; With chiral ammonium salt; isopropyl alcohol; In dichloromethane; at -70 ℃; for 40h;

trifluoroacetic anhydride; In dichloromethane;

DOI:10.1021/ol047698w

Reference yield:

trimethylsilyl cyanide (7677-24-9) + trifluoroacetic anhydride (407-25-0) + Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine (246509-62-6) → (S)-N-trifluoroacetyl-α-allylamino-3-methyl-phenyl-acetonitrile + (R)-N-trifluoroacetyl-α-allylamino-3-methyl-phenyl-acetonitrile

Guidance literature:

trimethylsilyl cyanide; Allyl-[1-m-tolyl-meth-(E)-ylidene]-amine; 2-salen-glucosaminyl-1β-(L-tert-Leu(NHBn)-urea) derivative; In methanol; toluene; at -50 ℃; for 24h;

trifluoroacetic anhydride; In methanol; toluene; at 20 ℃; for 3h; Further stages. Title compound not separated from byproducts.;

DOI:10.1002/adsc.200600370

upstream raw materials:

1-amino-2-propene

m-tolyl aldehyde

Refernces

• 1、 Zhang, Lei,Malinakova, Helena C.. "Copper-catalyzed multicomponent cascade process for the synthesis of hexahydro-1H-isoindolones". . p. 1484 - 1487. Retrieved 2007/10/03.