Phenylcarbamic acid phenyl ester

Base Information

• Chemical Name: Phenylcarbamic acid phenyl ester
• CAS No.: 4930-03-4
• Molecular Formula: C13H11NO2
• Molecular Weight: 213.236
• Mol file: 4930-03-4.mol

Synonyms:Phenyl carbanilate;phenyl-N-phenylurethane;N-phenyl phenyl carbamate;Carbanilic acid,phenyl ester;Phenyl phenylcarbamate;N-phenylphenoxycarboxamide;phenylcarbamic acid phenyl ester;

Chemical Property of Phenylcarbamic acid phenyl ester

Chemical Property:

• Vapor Pressure: 0.000434mmHg at 25°C
• Boiling Point: 315.6°C at 760 mmHg
• Flash Point: 144.6°C
• PSA: 38.33000
• Density: 1.222g/cm³
• LogP: 3.37050

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenylcarbamic acid phenyl ester

There total 51 articles about Phenylcarbamic acid phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

aniline (62-53-3) + phenyl chloroformate (1885-14-9) → phenyl N-phenylcarbamate (4930-03-4)

Guidance literature:

With triethylamine; In dichloromethane; for 3h;

DOI:10.1016/j.tet.2004.07.071

Reference yield: 100.0%

phenyl isocyanate (103-71-9) + phenol (108-95-2,27073-41-2) → phenyl N-phenylcarbamate (4930-03-4)

Guidance literature:

at 20 ℃; for 2h;

DOI:10.1246/cl.2004.1364

Reference yield: 98.0%

bis(phenyl) carbonate (102-09-0) + aniline (62-53-3) → phenyl N-phenylcarbamate (4930-03-4)

Guidance literature:

With isobutyric Acid; 1,3,5-tris(N,N-dimethylaminopropyl)-hexahydro-s-triazine; In toluene; at 55 ℃; for 48h;

upstream raw materials:

bis(phenyl) carbonate

N,N-diphenylurea

N-phenyl-1H-imidazole-1-carboxamide

phenol

Downstream raw materials:

malonanilic acid

2-acetyl-N-phenyl-malonamic acid ethyl ester

carbamic acid, phenyl-, 1-methylethyl ester

N-(benzyloxycarbonyl)aniline

Refernces

• 1、 Han, Yufei,Huang, Desheng,Xu, Sicong,Li, Lingling,Tian, Ye,Li, Shuo,Chen, Cong,Li, Yingxiu,Sun, Yanping,Hou, Yunlei,Sun, Yongjun,Qin, Mingze,Gong, Ping,Gao, Zibin,Zhao, Yanfang. "Ligand-based optimization to identify novel 2-aminobenzo[d]thiazole derivatives as potent sEH inhibitors with anti-inflammatory effects". . . Retrieved 2020/12/07.
• 2、 -. "AMPK agonist compound or pharmaceutically acceptable salt or ester or solvate thereof and application thereof". Paragraph 0125-0128. . Retrieved 2021/07/17.