3-chloro-4-(3'-chloro-4'-allyloxybenzyloxy)-phenylacetic acid

Base Information

• Chemical Name: 3-chloro-4-(3'-chloro-4'-allyloxybenzyloxy)-phenylacetic acid
• CAS No.: 60736-67-6
• Molecular Formula: C₁₈H₁₆Cl₂O₄
• Molecular Weight: 367.229
• Mol file: 60736-67-6.mol

Synonyms:3-chloro-4-(3'-chloro-4'-allyloxybenzyloxy)-phenylacetic acid

Chemical Property of 3-chloro-4-(3'-chloro-4'-allyloxybenzyloxy)-phenylacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 3-chloro-4-(3'-chloro-4'-allyloxybenzyloxy)-phenylacetic acid

There total 7 articles about 3-chloro-4-(3'-chloro-4'-allyloxybenzyloxy)-phenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

methyl 3-chloro-4-hydroxyphenylacetate (57017-95-5) → 3-chloro-4-(3'-chloro-4'-allyloxybenzyloxy)-phenylacetic acid (60736-67-6)

Guidance literature:

Reference yield:

2-monochlorophenol (95-57-8) → 3-chloro-4-(3'-chloro-4'-allyloxybenzyloxy)-phenylacetic acid (60736-67-6)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOEt

2: HCl, As₂O₃

3: (i) NaOEt, (ii) /BRN= 2050443/, (iii) aq. NaOH

With hydrogenchloride; sodium ethanolate; arsenic(III) trioxide;

DOI:10.1135/cccc19771723

Reference yield:

2-Chloroanisole (766-51-8) → 3-chloro-4-(3'-chloro-4'-allyloxybenzyloxy)-phenylacetic acid (60736-67-6)

Guidance literature:

Multi-step reaction with 4 steps

1: HCl, As₂O₃

3: (i) aq. HBr, (ii) /BRN= 1098229/, HCl

4: (i) NaOEt, (ii) /BRN= 2050443/, (iii) aq. NaOH

With hydrogenchloride; arsenic(III) trioxide;

DOI:10.1135/cccc19771723

upstream raw materials:

1-allyloxy-2-chloro-4-chloromethylbenzene

methyl 3-chloro-4-hydroxyphenylacetate

3-chloro-4-methoxybenzyl chloride

2-monochlorophenol