2-boronobenzaldehyde isonicotinoyl hydrazone

Base Information

• Chemical Name: 2-boronobenzaldehyde isonicotinoyl hydrazone
• CAS No.: 98018-50-9
• Molecular Formula: C₁₃H₁₂BN₃O₃
• Molecular Weight: 269.068
• Mol file: 98018-50-9.mol

Synonyms:2-boronobenzaldehyde isonicotinoyl hydrazone

Chemical Property of 2-boronobenzaldehyde isonicotinoyl hydrazone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-boronobenzaldehyde isonicotinoyl hydrazone

There total 2 articles about 2-boronobenzaldehyde isonicotinoyl hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

isoniazid (54-85-3,7640-37-1) + 2-formylbenzene boronic acid (40138-16-7) → 2-boronobenzaldehyde isonicotinoyl hydrazone (98018-50-9)

Guidance literature:

In ethanol; water; for 1h; Heating;

DOI:10.1002/anie.200604859

Reference yield: 80.0%

isoniazid (54-85-3,7640-37-1) + 2-formylbenzene boronic acid (40138-16-7) → 2-boronobenzaldehyde isonicotinoyl hydrazone (98018-50-9)

Guidance literature:

With sodium acetate; In methanol; water; soln. isonicotinic acid hydrazide in 0.1 M AcONa buffer (pH 4.5) was added to soln. boronic acid in MeOH and stirred at 100°C for 5 min; react. mixt. was cooled in ice, ppt. was filtered, washed with water anddried in vacuo;

DOI:10.1039/b705199a

Reference yield:

2-boronobenzaldehyde isonicotinoyl hydrazone (98018-50-9) → salinazid (495-84-1)

Guidance literature:

With dihydrogen peroxide; In phosphate buffer; N,N-dimethyl-formamide; at 24.84 ℃; for 2h; pH=7.29; Kinetics;

DOI:10.1002/anie.200604859

upstream raw materials:

isoniazid

2-formylbenzene boronic acid

Downstream raw materials:

salinazid