(S)-benzyl 3-ethyl-1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate

Base Information

• Chemical Name: (S)-benzyl 3-ethyl-1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate
• CAS No.: 1178876-41-9
• Molecular Formula: C₁₇H₂₆N₂O₄
• Molecular Weight: 322.404
• Mol file: 1178876-41-9.mol

Synonyms:(S)-benzyl 3-ethyl-1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate

Chemical Property of (S)-benzyl 3-ethyl-1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (S)-benzyl 3-ethyl-1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate

There total 1 articles about (S)-benzyl 3-ethyl-1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

N,O-dimethylhydroxylamine*hydrochloride (6638-79-5) + (S)-2-(benzyloxycarbonylamino)-3-ethylpentanoic acid (14328-77-9) → (S)-benzyl 3-ethyl-1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate (1178876-41-9)

Guidance literature:

With 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1016/j.bmc.2009.04.052

Reference yield:

(S)-benzyl 3-ethyl-1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate (1178876-41-9) + acetylenemagnesium bromide (4301-14-8) → (S)-benzyl 5-ethyl-3-oxohept-1-yn-4-ylcarbamate (1178876-45-3)

Guidance literature:

(S)-benzyl 3-ethyl-1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate; acetylenemagnesium bromide; In tetrahydrofuran; at -78 - 20 ℃; for 16.1667h;

With sodium hydrogen sulfate; water; In tetrahydrofuran; at 0 ℃;

DOI:10.1016/j.bmc.2009.04.052

upstream raw materials:

N,O-dimethylhydroxylamine*hydrochloride

(S)-2-(benzyloxycarbonylamino)-3-ethylpentanoic acid

Downstream raw materials:

(S)-benzyl 5-ethyl-3-oxohept-1-yn-4-ylcarbamate