Methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate

Base Information

• Chemical Name: Methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate
• CAS No.: 1236357-65-5
• Molecular Formula: C₁₂H₁₃BrO₂
• Molecular Weight: 269.138
• Hs Code.: 2916399090
• DSSTox Substance ID: DTXSID50695142
• Wikidata: Q82624201
• Mol file: 1236357-65-5.mol

Synonyms:1236357-65-5;METHYL 1-(4-BROMOPHENYL)CYCLOBUTANECARBOXYLATE;methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate;1-(4-BROMOPHENYL)CYCLOBUTANECARBOXYLIC ACID METHYL ESTER;SCHEMBL3052103;1-(4-Bromo-phenyl)-cyclobutanecarboxylic acid methyl ester;DTXSID50695142;LZYFYTYZRWWHCD-UHFFFAOYSA-N;MFCD18711569;PB28772;AS-36036;CS-0049270;A922046;METHYL1-(4-BROMOPHENYL)CYCLOBUTANECARBOXYLATE;Cyclobutanecarboxylic acid, 1-(4-bromophenyl)-, methyl ester

Chemical Property of Methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate

Chemical Property:

• Boiling Point: 308.6±35.0 °C(Predicted)
• Density: 1.436±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 268.00989
• Heavy Atom Count: 15
• Complexity: 240

Purity/Quality:

99%, ^*data from raw suppliers

Methyl1-(4-Bromophenyl)cyclobutanecarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC(=O)C1(CCC1)C2=CC=C(C=C2)Br

Technology Process of Methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate

There total 6 articles about Methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-(4-bromophenyl)cyclobutane-1-carboxylic acid → methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate (1236357-65-5)

Guidance literature:

With thionyl chloride; In methanol; at 70 ℃; Inert atmosphere;

Reference yield: 57.0%

(4-bromo-phenyl)-acetic acid methyl ester (41841-16-1) + 1,3-dibromo-propane (109-64-8) → methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate (1236357-65-5)

Guidance literature:

(4-bromo-phenyl)-acetic acid methyl ester; With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 0.166667h;

1,3-dibromo-propane; In tetrahydrofuran; at 20 ℃; for 24h;

Reference yield:

methanol (67-56-1) + 1-(4-bromophenyl)cyclobutane-1-carboxylic acid → methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate (1236357-65-5)

Guidance literature:

With thionyl chloride; at 0 - 60 ℃;

upstream raw materials:

(4-bromo-phenyl)-acetic acid methyl ester

1,3-dibromo-propane

4-Bromophenylacetonitrile

methanol

Downstream raw materials:

C₁₆H₁₇N₃O₂

C₂₂H₂₃N₃O₂

methyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutane-1-carboxylate

methyl 1-(4-(3-ethoxy-3-oxopropylamino)phenyl)cyclobutanecarboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1236357-65-5 1-(4-BroMo-phenyl)-cyclobutanecarboxylic acid Methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send