4-bromo-5-methoxy-2-nitro-phenol

Base Information

• Chemical Name: 4-bromo-5-methoxy-2-nitro-phenol
• CAS No.: 633357-97-8
• Molecular Formula: C₇H₆BrNO₄
• Molecular Weight: 248.033
• Mol file: 633357-97-8.mol

Synonyms:

Chemical Property of 4-bromo-5-methoxy-2-nitro-phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-bromo-5-methoxy-2-nitro-phenol

There total 8 articles about 4-bromo-5-methoxy-2-nitro-phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methoxy-6-nitro-phenol (704-14-3) → 4-bromo-5-methoxy-2-nitro-phenol (633357-97-8)

Guidance literature:

With chloroform; bromine;

DOI:10.1039/jr9350000946

Reference yield:

4-benzoyloxy-1-bromo-2-methoxy-benzene (855836-50-9) → 4-bromo-5-methoxy-2-nitro-phenol (633357-97-8)

Guidance literature:

With sodium hydroxide; Behandeln der mit wss. H₂SO₄ angesaeuerten Reaktionsloesung mit ueberschuessigem NaNO₂;

DOI:10.1039/jr9350000946

Reference yield:

O-methylresorcine (150-19-6) → 4-bromo-5-methoxy-2-nitro-phenol (633357-97-8)

Guidance literature:

Multi-step reaction with 2 steps

1: glacial acetic acid; fuming sulfuric acid / Behandeln des Reaktionsprodukts mit Salpetersaeure in Eisessig bei 0grad und anschliessendes Einleiten von ueberhitztem Wasserdampf

2: chloroform; bromine

With chloroform; sulfuric acid; bromine; acetic acid;

DOI:10.1039/jr9350000946

upstream raw materials:

3-methoxy-6-nitro-phenol

4-benzoyloxy-1-bromo-2-methoxy-benzene

chloroform

acetic acid

Downstream raw materials:

2,4-dibromo-3-methoxy-6-nitro-phenol

1-bromo-2,4-dimethoxy-5-nitrobenzene