tert-butyl 4-chloro-2-(2,3-dihydro-1,4-benzodioxin-5-ylcarbonyl)phenyl carbamate

Base Information

Chemical Name:tert-butyl 4-chloro-2-(2,3-dihydro-1,4-benzodioxin-5-ylcarbonyl)phenyl carbamate
CAS No.:937058-11-2
Molecular Formula:C₂₀H₂₀ClNO₅
Molecular Weight:389.835
Hs Code.:

Synonyms:tert-butyl 4-chloro-2-(2,3-dihydro-1,4-benzodioxin-5-ylcarbonyl)phenyl carbamate

Suppliers and Price of tert-butyl 4-chloro-2-(2,3-dihydro-1,4-benzodioxin-5-ylcarbonyl)phenyl carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 4-chloro-2-(2,3-dihydro-1,4-benzodioxin-5-ylcarbonyl)phenyl carbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl 4-chloro-2-(2,3-dihydro-1,4-benzodioxin-5-ylcarbonyl)phenyl carbamate

There total 3 articles about tert-butyl 4-chloro-2-(2,3-dihydro-1,4-benzodioxin-5-ylcarbonyl)phenyl carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 937058-10-1
tert-butyl 4-chloro-2-[2,3-dihydro-1,4-benzodioxin-5-yl(hydroxy)methyl]phenyl carbamate

: 937058-11-2
tert-butyl 4-chloro-2-(2,3-dihydro-1,4-benzodioxin-5-ylcarbonyl)phenyl carbamate

Guidance literature:: With manganese(IV) oxide; In dichloromethane; at 50 ℃;
DOI:10.1016/j.bmc.2012.02.054

Reference yield:

: 24677-78-9
2,3-dihydroxybenzaldehyde

: 937058-11-2
tert-butyl 4-chloro-2-(2,3-dihydro-1,4-benzodioxin-5-ylcarbonyl)phenyl carbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 3 h / 70 °C

2.1: sec.-butyllithium / tetrahydrofuran / -78 °C / Cooling with ice

2.2: 20 °C / Cooling with ice

2.3: 20 °C

3.1: manganese(IV) oxide / dichloromethane / 50 °C

With manganese(IV) oxide; sec.-butyllithium; potassium carbonate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2012.02.054

Reference yield:

: 29668-43-7
2,3-dihydro-benzo[1,4]dioxine-5-carbaldehyde

: 937058-11-2
tert-butyl 4-chloro-2-(2,3-dihydro-1,4-benzodioxin-5-ylcarbonyl)phenyl carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sec.-butyllithium / tetrahydrofuran / -78 °C / Cooling with ice

1.2: 20 °C / Cooling with ice

1.3: 20 °C

2.1: manganese(IV) oxide / dichloromethane / 50 °C

With manganese(IV) oxide; sec.-butyllithium; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2012.02.054