alpha-(Diphenylmethylene)benzeneacetaldehyde

Base Information

• Chemical Name: alpha-(Diphenylmethylene)benzeneacetaldehyde
• CAS No.: 25683-83-4
• Molecular Formula: C₂₁H₁₆O
• Molecular Weight: 284.357
• DSSTox Substance ID: DTXSID501274209
• Nikkaji Number: J2.181.272B
• Mol file: 25683-83-4.mol

Synonyms:SCHEMBL4693706;DTXSID501274209;25683-83-4;alpha-(Diphenylmethylene)benzeneacetaldehyde

Chemical Property of alpha-(Diphenylmethylene)benzeneacetaldehyde

Chemical Property:

• XLogP3: 5.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 284.120115130
• Heavy Atom Count: 22
• Complexity: 357

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=C(C2=CC=CC=C2)C3=CC=CC=C3)C=O

Technology Process of alpha-(Diphenylmethylene)benzeneacetaldehyde

There total 17 articles about alpha-(Diphenylmethylene)benzeneacetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,3,3-triphenyl-prop-2-en-1-ol (94866-53-2) → 2,3,3-triphenylacrylaldehyde (25683-83-4)

Guidance literature:

With manganese(IV) oxide; In benzene; for 4h;

DOI:10.1021/ja00299a036

Reference yield: 85.0%

iodobenzene (591-50-4) + phenylpropargyl aldehyde diethyl acetal (6142-95-6) + phenylboronic acid (98-80-6) → 2,3,3-triphenylacrylaldehyde (25683-83-4)

Guidance literature:

iodobenzene; phenylpropargyl aldehyde diethyl acetal; phenylboronic acid; With potassium hydrogencarbonate; bis(benzonitrile)palladium(II) dichloride; In water; N,N-dimethyl-formamide; at 100 ℃; for 12h;

With silica gel;

DOI:10.1021/jo048265+

Reference yield: 77.0%

4,4,5-Triphenyl-3-oxa-1-aza-bicyclo[3.1.0]hexan-2-one (64890-04-6) → benzophenone (119-61-9) + 2,3,3-triphenylacrylaldehyde (25683-83-4) + 2,2,3-triphenyl-1-azabicyclo<1.1.0>butane (89030-16-0)

Guidance literature:

With perdeuteriopyridine; In acetonitrile; at 20 ℃; for 25h; Product distribution; Irradiation; further bicyclocarbamates or -thiocarbamates;

upstream raw materials:

1,1,2-triphenylprop-1-ene

3-Azido-2.3.3-triphenyl-1-propyljodid

2,3,3-triphenyl-prop-2-en-1-ol

4,4,5-Triphenyl-3-oxa-1-aza-bicyclo[3.1.0]hexan-2-one

Downstream raw materials:

2,3,3-triphenylpropenal tosylhydrazone

2-(1,2,2-triphenylvinyl)-2H-pyran-4(3H)-one