Trifluoro-methanesulfonic acid 5-methyl-4-oxo-2-phenyl-2-o-tolyl-7-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-4H-benzo[1,3]dioxin-8-yl ester

Base Information

• Chemical Name: Trifluoro-methanesulfonic acid 5-methyl-4-oxo-2-phenyl-2-o-tolyl-7-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-4H-benzo[1,3]dioxin-8-yl ester
• CAS No.: 149913-01-9
• Molecular Formula: C₄₃H₃₂F₆O₁₄S₂
• Molecular Weight: 950.841
• Mol file: 149913-01-9.mol

Synonyms:Trifluoro-methanesulfonic acid 5-methyl-4-oxo-2-phenyl-2-o-tolyl-7-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-4H-benzo[1,3]dioxin-8-yl ester

Chemical Property of Trifluoro-methanesulfonic acid 5-methyl-4-oxo-2-phenyl-2-o-tolyl-7-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-4H-benzo[1,3]dioxin-8-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Trifluoro-methanesulfonic acid 5-methyl-4-oxo-2-phenyl-2-o-tolyl-7-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-4H-benzo[1,3]dioxin-8-yl ester

There total 10 articles about Trifluoro-methanesulfonic acid 5-methyl-4-oxo-2-phenyl-2-o-tolyl-7-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-4H-benzo[1,3]dioxin-8-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

Trifluoro-methanesulfonic acid 5-methyl-4-oxo-2-phenyl-2-o-tolyl-7-[(E)-2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-vinyl]-4H-benzo[1,3]dioxin-8-yl ester → Trifluoro-methanesulfonic acid 5-methyl-4-oxo-2-phenyl-2-o-tolyl-7-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-4H-benzo[1,3]dioxin-8-yl ester (149913-01-9)

Guidance literature:

With 1-methyl-pyrrolidin-2-one; hydrogenchloride; zinc;

Reference yield:

8-Hydroxy-5-methyl-2-phenyl-2-o-tolyl-benzo[1,3]dioxin-4-one (149912-98-1) → Trifluoro-methanesulfonic acid 5-methyl-4-oxo-2-phenyl-2-o-tolyl-7-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-4H-benzo[1,3]dioxin-8-yl ester (149913-01-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 99 percent / ICl, Et₃N

2: 95 percent

3: 95 percent / Pd(CF₃COO)2, P(C₆H₅)3, i-Pr₂NH, CF₃COOAg / tetrahydrofuran / 90 °C

4: 77 percent / Zn, conc. aq. HCl, N-methylpyrrolidinone

With 1-methyl-pyrrolidin-2-one; hydrogenchloride; palladium(II) trifluoroacetate; silver trifluoroacetate; Iodine monochloride; triethylamine; diisopropylamine; triphenylphosphine; zinc; In tetrahydrofuran;

Reference yield:

5-Methyl-2-phenyl-2-o-tolyl-benzo[1,3]dioxole-4-carboxylic acid (149912-97-0) → Trifluoro-methanesulfonic acid 5-methyl-4-oxo-2-phenyl-2-o-tolyl-7-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-4H-benzo[1,3]dioxin-8-yl ester (149913-01-9)

Guidance literature:

Multi-step reaction with 5 steps

1: 86 percent / CF₃COOH

2: 99 percent / ICl, Et₃N

3: 95 percent

4: 95 percent / Pd(CF₃COO)2, P(C₆H₅)3, i-Pr₂NH, CF₃COOAg / tetrahydrofuran / 90 °C

5: 77 percent / Zn, conc. aq. HCl, N-methylpyrrolidinone

With 1-methyl-pyrrolidin-2-one; hydrogenchloride; palladium(II) trifluoroacetate; silver trifluoroacetate; Iodine monochloride; triethylamine; diisopropylamine; triphenylphosphine; trifluoroacetic acid; zinc; In tetrahydrofuran;

upstream raw materials:

8-Hydroxy-5-methyl-2-phenyl-2-o-tolyl-benzo[1,3]dioxin-4-one

5-Methyl-2-phenyl-2-o-tolyl-benzo[1,3]dioxole-4-carboxylic acid

8-Hydroxy-7-iodo-5-methyl-2-phenyl-2-o-tolyl-benzo[1,3]dioxin-4-one

5-Methyl-2-phenyl-2-o-tolyl-benzo[1,3]dioxole-4-carboxylic acid tert-butylamide

Downstream raw materials:

2-Methoxy-6-methyl-3-trifluoromethanesulfonyloxy-4-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-benzoic acid methyl ester

G-2A

G-2N

2-Hydroxy-6-methyl-3-trifluoromethanesulfonyloxy-4-[2-(1,6,8-trimethoxy-9,10-dioxo-3-trifluoromethanesulfonyloxy-9,10-dihydro-anthracen-2-yl)-ethyl]-benzoic acid methyl ester