PHENYLSUCCINONITRILE

Base Information

• Chemical Name: PHENYLSUCCINONITRILE
• CAS No.: 13706-68-8
• Molecular Formula: C10H8 N2
• Molecular Weight: 156.187
• Hs Code.: 2926909090
• Mol file: 13706-68-8.mol

Synonyms:Butanedinitrile,phenyl- (9CI); Succinonitrile, phenyl- (6CI,7CI,8CI); Phenylsuccinonitrile

Chemical Property of PHENYLSUCCINONITRILE

Chemical Property:

• Vapor Pressure: 7E-05mmHg at 25°C
• Melting Point: 67-69°C
• Boiling Point: 160-165°C 0,5mm
• Flash Point: 170°C
• PSA: 47.58000
• Density: 1.093g/cm³
• LogP: 2.20746

Purity/Quality:

98%min ^*data from raw suppliers

Phenylsuccinonitrile ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22
• Safety Statements: 22-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PHENYLSUCCINONITRILE

There total 26 articles about PHENYLSUCCINONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trimethylsilyl cyanide (7677-24-9) + (E)-(1-deuterio-2-nitroethenyl)benzene (113436-59-2) → (+-)-phenylsuccinonitrile (13706-68-8)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; acetonitrile; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1002/chem.201404780

Reference yield: 93.0%

nitrostyrene (5153-67-3) + trimethylsilyl cyanide (7677-24-9) → (+-)-phenylsuccinonitrile (13706-68-8)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; acetonitrile; at 20 ℃; for 2h; Solvent; Reagent/catalyst; Inert atmosphere;

DOI:10.1002/chem.201404780

Reference yield: 93.0%

2-phenylmaleonitrile (79573-89-0) → (+-)-phenylsuccinonitrile (13706-68-8)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃;

upstream raw materials:

ethanol

1-chlorostyrene

potassium cyanide

ethyl 2,3-dicyano-3-phenylpropanoate

Downstream raw materials:

5-imino-3-phenyl-pyrrolidin-2-one

phenyl-succinic acid diamide

2-phenylsuccinic acid

3-phenylpyrrolidine

Refernces

• 1、 Zhang, Yue,Wei, Yi,Li, Shen,Ma, Jun-An. "Stereoselective One-Pot Synthesis of cis-1,2-Dicyanoalkenes from 1,1-Bis(benzenesulfonyl)alkenes and KCN". . p. 199 - 203. Retrieved 2019/01/04.
• 2、 Kiyokawa, Kensuke,Nagata, Takaya,Hayakawa, Junpei,Minakata, Satoshi. "Straightforward synthesis of 1,2-dicyanoalkanes from nitroalkenes and silyl cyanide mediated by tetrabutylammonium fluoride". supporting information. p. 1280 - 1285. Retrieved 2015/02/19.