10.1002/pola.27025
The research focuses on the synthesis, characterization, and evaluation of three novel dental monomers containing phosphonic acid groups, namely 1a, 2a, and 3a, for their potential use in dental adhesives. The purpose of this study was to develop monomers that exhibit hydrolytic stability, good polymerization rates, and strong adhesive properties. The researchers synthesized these monomers through a two-step process involving the reaction of α-aminophosphonates with acryloyl chloride or methacryloyl chloride, followed by hydrolysis using trimethylsilyl bromide. The synthesized monomers were characterized using various spectroscopic techniques, and their interactions with hydroxyapatite (HAP) were investigated. The study concluded that these phosphonic acid-containing (meth)acrylamides constitute a new class of monomers suitable for dental adhesives due to their hydrolytic stability, good polymerization rates, and adhesive properties. Key chemicals used in the synthesis process included diethyl amino(phenyl)methylphosphonate, diethyl 1-aminoheptylphosphonate, acryloyl chloride, methacryloyl chloride, trimethylsilyl bromide, and various solvents and reagents for purification and characterization.