5-chloro-6-methyl-4-nitro-2,1,3-benzoselenadiazole

Base Information

• Chemical Name: 5-chloro-6-methyl-4-nitro-2,1,3-benzoselenadiazole
• CAS No.: 147021-84-9
• Molecular Formula: C₇H₄ClN₃O₂Se
• Molecular Weight: 276.541
• Mol file: 147021-84-9.mol

Synonyms:5-chloro-6-methyl-4-nitro-2,1,3-benzoselenadiazole

Chemical Property of 5-chloro-6-methyl-4-nitro-2,1,3-benzoselenadiazole

Chemical Property:

• Solubility.: Methanol

Purity/Quality:

5-Chloro-6-methyl-4-nitro-2,1,3-benzoselenadiazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Intermediate in the synthesis of mutagenic methyl substituted 2-amino-3H-imidazo[4,5-f]quinoxalines.

Technology Process of 5-chloro-6-methyl-4-nitro-2,1,3-benzoselenadiazole

There total 2 articles about 5-chloro-6-methyl-4-nitro-2,1,3-benzoselenadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

5-chloro-6-methyl-2,1,3-benzoselenadiazole (2255-94-9) → 5-chloro-6-methyl-4-nitro-2,1,3-benzoselenadiazole (147021-84-9) + 6-chloro-5-methyl-4-nitro-2,1,3-benzoselenadiazole

Guidance literature:

With sulfuric acid; nitric acid; at 0 - 20 ℃; for 1h;

Reference yield:

4-chloro-5-methylbenzene-1,2-diamine (63155-04-4) → 5-chloro-6-methyl-4-nitro-2,1,3-benzoselenadiazole (147021-84-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / aq. HCl, SeO₂ / 80 °C

2: 56 percent / conc. H₂SO₄, conc. HNO₃ / 1 h / 0 - 20 °C

With hydrogenchloride; selenium(IV) oxide; sulfuric acid; nitric acid;

Reference yield: 82.0%

5-chloro-6-methyl-4-nitro-2,1,3-benzoselenadiazole (147021-84-9) + methylamine (74-89-5) → 6-methyl-5-methylamino-4-nitro-2,1,3-benzoselenadiazole (149703-56-0)

Guidance literature:

In 2-methoxy-ethanol; water; for 0.166667h; Heating;

upstream raw materials:

5-chloro-6-methyl-2,1,3-benzoselenadiazole

4-chloro-5-methylbenzene-1,2-diamine

Downstream raw materials:

4-chloro-5-methyl-3-nitro-1,2-benzenediamine

5-chloro-4-methyl-3-nitro-1,2-benzenediamine

6-methyl-5-methylamino-4-nitro-2,1,3-benzoselenadiazole

2-amino-3,4-dimethyl-3H-imidazo<4,5-f>quinoxaline

Refernces