Sulfaethidole

Base Information

Chemical Name:Sulfaethidole
CAS No.:94-19-9
Molecular Formula:C10H12 N4 O2 S2
Molecular Weight:284.363
Hs Code.:2935009090
European Community (EC) Number:202-312-4
UNII:R77Q4O5ZMD
DSSTox Substance ID:DTXSID4046286
Nikkaji Number:J182.099K
Wikidata:Q27185990
NCI Thesaurus Code:C152455
ChEMBL ID:CHEMBL1355299
Mol file:94-19-9.mol

Synonyms:berlophen;sulfaethidole;sulfaethidole monosodium salt

Suppliers and Price of Sulfaethidole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide
1g
$ 305.00

Aronis compounds
4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
5g
$ 371.00

Aronis compounds
4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
10g
$ 501.00

American Custom Chemicals Corporation
4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE 98.00%
500MG
$ 762.30

AK Scientific
4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide
1g
$ 461.00

Total 10 raw suppliers

Chemical Property of Sulfaethidole

Chemical Property:

Vapor Pressure:1.85E-10mmHg at 25°C
Melting Point:185.5-186.0°
Refractive Index:1.6440 (estimate)
Boiling Point:508.5°C at 760 mmHg
PKA:pKa 5.36(H2O t = 37) (Uncertain)
Flash Point:261.3°C
PSA：134.59000
Density:1.499g/cm³
LogP:3.21850
Water Solubility.:215mg/L(20 oC)
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:284.04016799
Heavy Atom Count:18
Complexity:363

Purity/Quality:

97% ^*data from raw suppliers

4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=NN=C(S1)NS(=O)(=O)C2=CC=C(C=C2)N
Therapeutic Function Antibacterial

Technology Process of Sulfaethidole

There total 8 articles about Sulfaethidole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 76170-72-4
2-(4-Nitrobenzenesulfonamido)-5-ethyl-1,3,4-thiadiazole

: 94-19-9
sulfaethidole

Guidance literature:: With tin(II) chloride dihdyrate; In ethyl acetate; for 36h; Reflux;
DOI:10.1021/ml400112h

Reference yield: 69.0%

: 1037-51-0
N-(4-(N-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide

: 94-19-9
sulfaethidole

Guidance literature:: N-(4-(N-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide; With hydrogenchloride; In water; for 0.5h; Reflux;

With sodium carbonate; In water;
DOI:10.1016/j.bmc.2011.01.049

Reference yield:

: 100-05-0
4-nitrobenzenediazonium chloride

: 94-19-9
sulfaethidole

Guidance literature:: Multi-step reaction with 3 steps

1: SO₂ / CuSO₄ / acetic acid / 6 - 20 °C

2: chlorobenzene / 2 h / 115 - 120 °C

3: Fe, NH₄Cl / H₂O / 7 h / Heating

With sulfur dioxide; iron; ammonium chloride; copper(II) sulfate; In water; acetic acid; chlorobenzene;
DOI:10.1007/BF01156380