1H-Imidazole, 1-ethyl-2-(6-methoxy-2-benzofuranyl)-, monohydrochloride

Base Information

Chemical Name:1H-Imidazole, 1-ethyl-2-(6-methoxy-2-benzofuranyl)-, monohydrochloride
CAS No.:150985-52-7
Molecular Formula:C₁₄H₁₄N₂O₂*ClH
Molecular Weight:278.738
Hs Code.:
DSSTox Substance ID:DTXSID60164677
ChEMBL ID:CHEMBL4864517
Mol file:150985-52-7.mol

Synonyms:150985-52-7;1H-Imidazole, 1-ethyl-2-(6-methoxy-2-benzofuranyl)-, monohydrochloride;1-Ethyl-2-(6-methoxyfuran-2-yl)imidazole hydrochloride;CHEMBL4864517;1-Ethyl-2-(6-methoxy-2-benzofuranyl)-1H-imidazole monohydrochloride;1-ethyl-2-(6-methoxy-1-benzofuran-2-yl)imidazole;hydrochloride;SCHEMBL9295364;DTXSID60164677;BDBM50572705;LS-78706;1-ethyl-2-(6-methoxybenzofuran-2-yl)imidazole hydrochloride

Suppliers and Price of 1H-Imidazole, 1-ethyl-2-(6-methoxy-2-benzofuranyl)-, monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-ETHYL-2-(6-METHOXY-2-BENZOFURANYL)-1H-IMIDAZOLE MONOHYDROCHLORIDE 95.00%
5MG
$ 496.28

Total 1 raw suppliers

Chemical Property of 1H-Imidazole, 1-ethyl-2-(6-methoxy-2-benzofuranyl)-, monohydrochloride

Chemical Property:

Vapor Pressure:4.6E-07mmHg at 25°C
Boiling Point:414°Cat760mmHg
Flash Point:204.2°C
PSA：40.19000
Density:g/cm³
LogP:4.12680
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:278.0822054
Heavy Atom Count:19
Complexity:287

Purity/Quality:: 1-ETHYL-2-(6-METHOXY-2-BENZOFURANYL)-1H-IMIDAZOLE MONOHYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C=CN=C1C2=CC3=C(O2)C=C(C=C3)OC.Cl

Technology Process of 1H-Imidazole, 1-ethyl-2-(6-methoxy-2-benzofuranyl)-, monohydrochloride

There total 7 articles about 1H-Imidazole, 1-ethyl-2-(6-methoxy-2-benzofuranyl)-, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 74-96-4
ethyl bromide

: 2-(6-methoxybenzofuran-2-yl)-1H-imidazole hydrochloride

: 150985-52-7
1-ethyl-2-(6-methoxybenzofuran-2-yl)-1H-imidazole hydrochloride

Guidance literature:: 2-(6-methoxybenzofuran-2-yl)-1H-imidazole hydrochloride; With sodium hydroxide;

With sodium hydride; In N,N-dimethyl-d₆-formamide; mineral oil; at 20 ℃; for 0.5h;

ethyl bromide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.75h;
DOI:10.1016/j.ejmech.2021.113540

Reference yield:

: 35351-48-5
6-methoxy-2-benzofurancarbonitrile

: 150985-52-7
1-ethyl-2-(6-methoxybenzofuran-2-yl)-1H-imidazole hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogenchloride / diethyl ether / 48 h / 4 °C

2.1: methanol / 16 h / 60 °C

3.1: hydrogenchloride / water / 16 h / 60 °C

4.1: sodium hydroxide

4.2: 0.5 h / 20 °C

4.3: 0.75 h / 0 - 20 °C

With hydrogenchloride; sodium hydroxide; In methanol; diethyl ether; water;
DOI:10.1016/j.ejmech.2021.113540

Reference yield:

: methyl 6-methoxybenzofuran-2-carbimididate hydrochloride

: 150985-52-7
1-ethyl-2-(6-methoxybenzofuran-2-yl)-1H-imidazole hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: methanol / 16 h / 60 °C

2.1: hydrogenchloride / water / 16 h / 60 °C

3.1: sodium hydroxide

3.2: 0.5 h / 20 °C

3.3: 0.75 h / 0 - 20 °C

With hydrogenchloride; sodium hydroxide; In methanol; water;
DOI:10.1016/j.ejmech.2021.113540