Technology Process of 4-(3-allyl-2-methoxyphenyl)-N,N'-di-tert-butoxycarbonyltryptamine
There total 11 articles about 4-(3-allyl-2-methoxyphenyl)-N,N'-di-tert-butoxycarbonyltryptamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); caesium carbonate;
In
1,2-dimethoxyethane;
DOI:10.1016/S0040-4039(00)01121-7
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 85 percent / K2CO3 / acetone / Heating
2.1: t-BuLi / hexane; tetrahydrofuran / 0.5 h / -78 °C
2.2: hexane; tetrahydrofuran / 1 h / 20 °C
3.1: 0.6 g / aq. HCl
4.1: 85 percent / aq. Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane / Heating
With
hydrogenchloride; tert.-butyl lithium; sodium carbonate; potassium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; 1,2-dimethoxyethane; hexane; acetone;
4.1: Suzuki coupling;
DOI:10.1039/b510653b
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 100 percent / Et2AlCl / hexane / 2.5 h / 20 °C
2.1: 85 percent / K2CO3 / acetone / Heating
3.1: t-BuLi / hexane; tetrahydrofuran / 0.5 h / -78 °C
3.2: hexane; tetrahydrofuran / 1 h / 20 °C
4.1: 0.6 g / aq. HCl
5.1: 85 percent / aq. Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane / Heating
With
hydrogenchloride; tert.-butyl lithium; diethylaluminium chloride; sodium carbonate; potassium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; 1,2-dimethoxyethane; hexane; acetone;
1.1: Claisen rearrangement / 5.1: Suzuki coupling;
DOI:10.1039/b510653b
