di-tert-butyl 2,2'-(2-bromo-5-(4-nitrophenyl)pentylazanediyl)diacetate

Base Information

• Chemical Name: di-tert-butyl 2,2'-(2-bromo-5-(4-nitrophenyl)pentylazanediyl)diacetate
• CAS No.: 1258945-71-9
• Molecular Formula: C₂₃H₃₅BrN₂O₆
• Molecular Weight: 515.445
• Mol file: 1258945-71-9.mol

Synonyms:di-tert-butyl 2,2'-(2-bromo-5-(4-nitrophenyl)pentylazanediyl)diacetate

Chemical Property of di-tert-butyl 2,2'-(2-bromo-5-(4-nitrophenyl)pentylazanediyl)diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di-tert-butyl 2,2'-(2-bromo-5-(4-nitrophenyl)pentylazanediyl)diacetate

There total 2 articles about di-tert-butyl 2,2'-(2-bromo-5-(4-nitrophenyl)pentylazanediyl)diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

{tert-butoxycarbonylmethyl-[1-hydroxymethyl-4-(4-nitrophenyl)butyl]amino}acetic acid tert-butyl ester (1142811-83-3) → di-tert-butyl 2,2'-(2-bromo-5-(4-nitrophenyl)pentylazanediyl)diacetate (1258945-71-9)

Guidance literature:

With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; regiospecific reaction;

DOI:10.1039/c0cc05707j

Reference yield: 66.0%

→ di-tert-butyl 2,2'-(2-bromo-5-(4-nitrophenyl)pentylazanediyl)diacetate (1258945-71-9)

Guidance literature:

Reference yield: 100.0%

di-tert-butyl 2,2'-(2-bromo-5-(4-nitrophenyl)pentylazanediyl)diacetate (1258945-71-9) → tert-butyl 2-[(1-{4,7-bis[2-(tert-butoxy)-2-oxoethyl]-1,4,7-triazonan-1-yl}-5-[4-nitrophenyl]pentan-2-yl)[2-(tert-butoxy)-2-oxoethyl]amino]acetate (1258946-46-1)

Guidance literature:

With silver perchlorate; In chloroform-d1; at -10 ℃; for 1h;

upstream raw materials:

{tert-butoxycarbonylmethyl-[1-hydroxymethyl-4-(4-nitrophenyl)butyl]amino}acetic acid tert-butyl ester

Downstream raw materials:

{2-[3-(4-nitrophenyl)-propyl]-6-oxomorpholin-4-yl}acetic acid tert-butyl ester

tert-butyl 2-[(1-{4,7-bis[2-(tert-butoxy)-2-oxoethyl]-1,4,7-triazonan-1-yl}-5-[4-nitrophenyl]pentan-2-yl)[2-(tert-butoxy)-2-oxoethyl]amino]acetate

tert-butyl-2-[(1-{4,7-bis[2-(tert-butoxy)-2-oxoethyl]-1,4,7-triazonan-1-yl}-5-[4-(hydroxyl-nitro)phenyl]-pentan-2-yl)[2-(tert-butoxy)-2-oxoethyl]amino]acetate

3p-C-NETA