Technology Process of N-2-[(Nε-Z-L-lysyl)]aminoethyl-N,N-di-n-hexadecylamine
There total 1 articles about N-2-[(Nε-Z-L-lysyl)]aminoethyl-N,N-di-n-hexadecylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C53H98N4O5;
With
trifluoroacetic acid;
In
dichloromethane;
at 0 - 20 ℃;
for 5h;
With
triethylamine;
In
dichloromethane;
at 20 ℃;
for 0.25h;
Product distribution / selectivity;
- Guidance literature:
-
BOC-L-aspartic acid 4-benzyl ester;
With
carbonic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester; dicyclohexyl-carbodiimide;
In
dichloromethane;
at 0 ℃;
for 0.5h;
N-2-[(Nε-Z-L-lysyl)]aminoethyl-N,N-di-n-hexadecylamine;
dmap;
In
dichloromethane;
at 20 ℃;
for 16h;
- Guidance literature:
-
2-((t-butyldiphenylsilyl)oxy)acetic acid;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane; N,N-dimethyl-formamide;
for 0.5h;
Cooling with ice;
Inert atmosphere;
N-2-[(Nε-Z-L-lysyl)]aminoethyl-N,N-di-n-hexadecylamine;
In
dichloromethane; N,N-dimethyl-formamide;
at 20 ℃;
Inert atmosphere;
