2-oxo-3-deoxygalactonic acid

Base Information

• Chemical Name: 2-oxo-3-deoxygalactonic acid
• CAS No.: 56742-44-0
• Molecular Formula: C6H10O6
• Molecular Weight: 178.142
• Mol file: 56742-44-0.mol

Synonyms:Dg-threo-3-Desoxy-[2]hexulosonsaeure;3-Deoxy-D-threo-2-hexulosesaeure;2-Oxo-3-desoxy-D-galaktonsaeure;D-2-keto-3-deoxygalactonate;Dg-threo-3-deoxy-[2]hexulosonic acid;(4R,5R)-4,5,6-Trihydroxy-2-oxo-hexanoic acid;2-Oxo-3-desoxy-galactonsaeure;

Chemical Property of 2-oxo-3-deoxygalactonic acid

Chemical Property:

• Vapor Pressure: 1.05E-10mmHg at 25°C
• Boiling Point: 467.5°C at 760 mmHg
• Flash Point: 250.6°C
• PSA: 115.06000
• Density: 1.582g/cm³
• LogP: -2.25570

Purity/Quality:

99% ^*data from raw suppliers

3-Deoxy-2-keto-D-galactonate lithium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-oxo-3-deoxygalactonic acid

There total 4 articles about 2-oxo-3-deoxygalactonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-Glyceraldehyde (453-17-8,367-47-5,26793-98-6) + 2-oxo-propionic acid (127-17-3) → (4R,5R)-3-deoxy-2-hexulosonic acid (56742-44-0) + 4,5,6-trihydroxy-2-oxohexanoic acid (17510-99-5)

Guidance literature:

With 2-keto-3-deoxygluconate aldolase from Sulfolobus acidocaldarius; at 50 ℃; Reagent/catalyst; stereoselective reaction; Enzymatic reaction;

DOI:10.1002/cctc.201300785

Reference yield:

D-Glyceraldehyde (453-17-8,367-47-5,26793-98-6) + sodium pyruvate (113-24-6) → (4R,5R)-3-deoxy-2-hexulosonic acid (56742-44-0) + 4,5,6-trihydroxy-2-oxohexanoic acid (17510-99-5)

Guidance literature:

With Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase; sodium phosphate; at 70 ℃; pH=6; Enzyme kinetics;

DOI:10.1039/b413255f

Reference yield:

Oxalacetic acid (328-42-7) + D-Glyceraldehyde (453-17-8,367-47-5,26793-98-6) → (4R,5R)-3-deoxy-2-hexulosonic acid (56742-44-0) + 4,5,6-trihydroxy-2-oxohexanoic acid (17510-99-5)

Guidance literature:

Multistep reaction; (i) aq. KOH, (ii) (decarboxylation);

DOI:10.1016/S0008-6215(00)80155-X

upstream raw materials:

Oxalacetic acid

D-Glyceraldehyde

sodium pyruvate

2-oxo-propionic acid

Downstream raw materials:

2-deoxy-D-lyxonic acid

furan-2-yl-oxo-acetic acid