methanesulfonic acid 2-(2-nitro-4-trifluoromethylphenylamino)-butyl ester

Base Information

• Chemical Name: methanesulfonic acid 2-(2-nitro-4-trifluoromethylphenylamino)-butyl ester
• CAS No.: 871834-52-5
• Molecular Formula: C₁₂H₁₅F₃N₂O₅S
• Molecular Weight: 356.323

Synonyms:methanesulfonic acid 2-(2-nitro-4-trifluoromethylphenylamino)-butyl ester

Chemical Property of methanesulfonic acid 2-(2-nitro-4-trifluoromethylphenylamino)-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methanesulfonic acid 2-(2-nitro-4-trifluoromethylphenylamino)-butyl ester

There total 2 articles about methanesulfonic acid 2-(2-nitro-4-trifluoromethylphenylamino)-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-(2-nitro-4-trifluoromethylphenylamino)-butan-1-ol (871834-51-4) + methanesulfonyl chloride (124-63-0) → methanesulfonic acid 2-(2-nitro-4-trifluoromethylphenylamino)-butyl ester (871834-52-5)

Guidance literature:

2-(2-nitro-4-trifluoromethylphenylamino)-butan-1-ol; methanesulfonyl chloride; With pyridine; In dichloromethane; at 20 ℃; for 3h;

With hydrogenchloride; In DMF (N,N-dimethyl-formamide); dichloromethane; water;

With sodium hydrogencarbonate; In DMF (N,N-dimethyl-formamide); dichloromethane; water;

Reference yield:

1-fluoro-2-nitro-4-trifluoromethyl-benzene (367-86-2) → methanesulfonic acid 2-(2-nitro-4-trifluoromethylphenylamino)-butyl ester (871834-52-5)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 20 - 80 °C

2: pyridine / CH₂Cl₂

With pyridine; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2007.01.112

Reference yield:

methanesulfonic acid 2-(2-nitro-4-trifluoromethylphenylamino)-butyl ester (871834-52-5) → C12H17N2O3SF3

Guidance literature:

With hydrogen; palladium on activated charcoal; In 1-methyl-pyrrolidin-2-one;

DOI:10.1016/j.bmcl.2007.01.112

upstream raw materials:

2-(2-nitro-4-trifluoromethylphenylamino)-butan-1-ol

methanesulfonyl chloride

1-fluoro-2-nitro-4-trifluoromethyl-benzene

Downstream raw materials:

1-(3,5-bis-trifluoromethylbenzyl)-3-ethyl-7-trifluoromethyl-1,2,3,4-tetrahydroquinoxaline

4-(3,5-Bis-trifluoromethyl-benzyl)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoxaline-1-carboxylic acid ethyl ester

(3,5-bis-trifluoromethylphenyl)-(3-ethyl-7-trifluoromethyl-3,4-dihydro-2H-quinoxalin-1-yl)-acetonitrile

C₂₁H₁₇F₉N₆

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 871834-52-5 methanesulfonic acid 2-(2-nitro-4-trifluoromethylphenylamino)-butyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send