Nandrolone phenpropionate

Base Information

• Chemical Name: Nandrolone phenpropionate
• CAS No.: 62-90-8
• Molecular Formula: C27H34O3
• Molecular Weight: 406.565
• Hs Code.: 2942000000
• European Community (EC) Number: 200-551-9
• NSC Number: 23162
• UNII: KF7Z9K2T3W
• DSSTox Substance ID: DTXSID2023353
• Nikkaji Number: J8.621E
• Wikipedia: Nandrolone_phenylpropionate
• Wikidata: Q4312826
• NCI Thesaurus Code: C66218
• Pharos Ligand ID: Y3AKKS4B7ZS1
• Metabolomics Workbench ID: 43235
• ChEMBL ID: CHEMBL1200412
• Mol file: 62-90-8.mol

Synonyms:17 beta-hydroxyestr-4-en-3-one hydrocinnamate;Durabolin;Fenobolin;nandrolone phenpropionate;nandrolone phenpropionate, (17alpha)-isomer;Nerobolil;Nerobolyl;norandrolone phenylpropionate;nortestosterone phenylpropionate;NSC-23162E

Chemical Property of Nandrolone phenpropionate

Chemical Property:

• Appearance/Colour: White or milky crystalline powder
• Vapor Pressure: 5.12E-12mmHg at 25°C
• Melting Point: 93-99oC
• Refractive Index: 1.577
• Boiling Point: 546.9 °C at 760 mmHg
• Flash Point: 234.6 °C
• PSA: 43.37000
• Density: 1.14 g/cm³
• LogP: 5.67280
• Storage Temp.: Controlled Substance, -20?C Freezer
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 406.25079494
• Heavy Atom Count: 30
• Complexity: 703

Purity/Quality:

99% ^*data from raw suppliers

Nandrolone phenpropionate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-40
• Safety Statements: 23-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCC3C(C1CCC2OC(=O)CCC4=CC=CC=C4)CCC5=CC(=O)CCC35
• Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2OC(=O)CCC4=CC=CC=C4)CCC5=CC(=O)CC[C@H]35
• Indications: In the field of dermatology, it is mainly applied as a adjuvant treatment method for treating the negative nitrogen balance caused by high dose of corticosteroids, while increasing the protein in food; it is also used for treating exfoliative dermatitis, pemphigus, dermatomyositis, scleroderma, and senile pruritus. In addition, it can also used for treating severe burns, malignant tumor before and after surgery, refractory fractures and severe osteoporosis, premature children, significant growth retardation, dwarfism, severe malnutrition, loss of appetite, diarrhea and other serious chronic wasting diseases. In the mean time of other treatments, the product can be administrated. It can also alleviate the symptoms of inoperable breast cancer. It is also suitable to be applied to functional uterine bleeding, and uterine fibroids.
• Drug Interactions: 1. Using it in combination with oral anticoagulant drug can improve the efficacy of the latter one and increase the tendency of increased bleeding. 2. Anabolic steroids can reduce glucose tolerance; diabetic patients should pay attention to adjust the dose insulin or orally administrated amount of hypoglycemic medicine during the treatment. 3. Others are the same as methyltestosterone.
• Uses: Anabolic steroid; androgen.

Technology Process of Nandrolone phenpropionate

There total 10 articles about Nandrolone phenpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

19-nortestosterone (434-22-0) + 3-phenyl-propenal (104-55-2) → activin (62-90-8)

Guidance literature:

With bis(1-butyl-3-methylimidazolium) tungstate; In 1,4-dioxane; at 120 ℃; for 2.5h;

Reference yield: 74.0%

19-nortestosterone (434-22-0) + 3-Phenylpropionic acid (501-52-0) → activin (62-90-8)

Guidance literature:

With 18-crown-6 ether; potassium carbonate; 2-(trimethylsilyl)phenyl trifluoromethanesulfonate; cesium fluoride; In acetonitrile; at 70 ℃; for 8h;

DOI:10.1021/acs.orglett.1c02702

Reference yield:

19-nortestosterone (434-22-0) → activin (62-90-8)

Guidance literature:

With hydrogenchloride; sodium hydroxide; In pyridine;

upstream raw materials:

19-nortestosterone

octanol

3-methoxy-17-hydroxyestra-2,5⁽¹⁰⁾-diene

3-phenyl-propenal

Refernces

• 1、 -. "Ionic liquid catalytic synthesis of styrene-acrylic acid ester derivative of the method (by machine translation)". Paragraph 0035. . Retrieved 2019/05/08.