4-[3-({[4'-(4-amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]amino}-sulphonyl)propyl]morpholin-4-ium formate

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Chemical Name:4-[3-({[4'-(4-amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]amino}-sulphonyl)propyl]morpholin-4-ium formate
CAS No.:1033435-49-2
Molecular Formula:CH₂O₂*C₂₉H₃₆ClN₃O₅S
Molecular Weight:620.167
Hs Code.:

Synonyms:4-[3-({[4'-(4-amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]amino}-sulphonyl)propyl]morpholin-4-ium formate

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Chemical Property of 4-[3-({[4'-(4-amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]amino}-sulphonyl)propyl]morpholin-4-ium formate

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Technology Process of 4-[3-({[4'-(4-amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]amino}-sulphonyl)propyl]morpholin-4-ium formate

There total 1 articles about 4-[3-({[4'-(4-amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]amino}-sulphonyl)propyl]morpholin-4-ium formate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 110-91-8,99108-56-2
morpholine

: 64-18-6
formic acid

: 1033436-22-4
N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide

: 1033435-49-2
4-[3-({[4'-(4-amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]amino}-sulphonyl)propyl]morpholin-4-ium formate

Guidance literature:: morpholine; N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide; In tetrahydrofuran; at 20 - 60 ℃; for 22h;

formic acid; In water; acetonitrile;