N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide

Base Information

Chemical Name:N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide
CAS No.:1033436-22-4
Molecular Formula:C₂₅H₂₈BrClN₂O₄S
Molecular Weight:567.931
Hs Code.:

Synonyms:N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide

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Chemical Property of N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide

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Technology Process of N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide

There total 1 articles about N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89123-01-3
3-bromopropanesulfonyl chloride

: 1033435-30-1
4-amino-3-(3'-amino-2-chloro-5-methylbiphenyl-4-yl)-1-oxaspiro[4.5]dec-3-en-2-one

: 1033436-22-4
N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide

: N-[4'-(4-amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-chloropropane-1-sulphonamide

Guidance literature:: With pyridine; In tetrahydrofuran; at 20 ℃; for 18h;

Reference yield: 53.0%

: 110-91-8,99108-56-2
morpholine

: 64-18-6
formic acid

: 1033436-22-4
N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide

: 1033435-49-2
4-[3-({[4'-(4-amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]amino}-sulphonyl)propyl]morpholin-4-ium formate

Guidance literature:: morpholine; N-[4'-(4-Amino-2-oxo-1-oxaspiro[4.5]dec-3-en-3-yl)-2'-chloro-5'-methylbiphenyl-3-yl]-3-bromopropane-1-sulphonamide; In tetrahydrofuran; at 20 - 60 ℃; for 22h;

formic acid; In water; acetonitrile;