Aminomethanesulfonic acid

Base Information

• Chemical Name: Aminomethanesulfonic acid
• CAS No.: 13881-91-9
• Molecular Formula: CH5NO3S
• Molecular Weight: 111.122
• Hs Code.: 29211980
• European Community (EC) Number: 237-649-6,230-076-2
• NSC Number: 209983
• UNII: OLA224Z482
• DSSTox Substance ID: DTXSID2065670
• Nikkaji Number: J93.626J
• Wikidata: Q27285722
• ChEMBL ID: CHEMBL1741886
• Mol file: 13881-91-9.mol

Synonyms:aminomethanesulfonic acid

Chemical Property of Aminomethanesulfonic acid

Chemical Property:

• Appearance/Colour: White powder
• Melting Point: 184 °C (dec.)(lit.)
• Refractive Index: 1.526
• PKA: pK1: 5.57(+1) (25°C)
• PSA: 88.77000
• Density: 1.652 g/cm³
• LogP: 0.57150
• Storage Temp.: Store at RT.
• Solubility.: 17g/l
• Water Solubility.: Soluble in water. (17 g/L) at 17°C
• XLogP3: -4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 110.99901420
• Heavy Atom Count: 6
• Complexity: 107

Purity/Quality:

≥99% ^*data from raw suppliers

Aminomethanesulfonic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45-afety

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Uses -> Biochemical Research
• Canonical SMILES: C(N)S(=O)(=O)O
• Uses: Aminomethanesulfonic acid can be used as a reactant to synthesize: 1-Sulfomethyltetrazole-5-thiol disodium salts, which are useful key intermediates for the preparation of cefonicid sodium. Tridentate N-(2-hydroxybenzyl)aminomethane sulfonic acid Schiff-base ligand by reacting with salicylaldehyde. It can also be used to functionalize the surface of single-walled carbon nanotubes (SWCNT) or porous metal-organic frameworks (MOF) to introduce the sulfonic acid functional groups for the preparation of nanocomposites.

Technology Process of Aminomethanesulfonic acid

There total 7 articles about Aminomethanesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.57%

hexamethylenetetramine (100-97-0) → aminomethanesulfonic acid (13881-91-9)

Guidance literature:

With sulfur dioxide; water; at 0 ℃;

DOI:10.1134/S1070363211030352

Reference yield: 15.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) → aminomethanesulfonic acid (13881-91-9)

Guidance literature:

With ammonium hydroxide; sodium hydrogensulfite;

DOI:10.1021/jm00402a012

Reference yield:

→ aminomethanesulfonic acid (13881-91-9) + (3-nitro-phenacylamino)-methanesulfonic acid

Guidance literature:

With sulfur dioxide; water; at 45 ℃;

upstream raw materials:

formaldehyd

ammonia

water

sodium hydroxymethanesulfonate monohydrate

Downstream raw materials:

6-phenyl-[1,3]oxazinane

bis-(6-phenyl-dihydro-[1,3]oxazin-3-yl)-methane

glycine

chloromethane sulfonic acid