2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl propionate

Base Information

Chemical Name:2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl propionate
CAS No.:415907-59-4
Molecular Formula:C₂₁H₂₅N₃O₂
Molecular Weight:351.448
Hs Code.:

Synonyms:2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl propionate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl propionate

Chemical Property:

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Technology Process of 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl propionate

There total 6 articles about 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 415907-58-3
2-{4-[(3-amino-4,6-dimethyl-2-pyridinyl)amino]phenyl}ethanol

: 79-03-8
propionyl chloride

: 415907-59-4
2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl propionate

Guidance literature:: In toluene; at 0 ℃; for 2h; Heating / reflux;

Reference yield:

: 415907-57-2
2-{4-[(4,6-dimethyl-3-nitro-2-pyridinyl)amino]phenyl}ethanol

: 415907-59-4
2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl propionate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 6 h / 20 °C

2: toluene / 2 h / 0 °C / Heating / reflux

With hydrogen; palladium 10% on activated carbon; In ethyl acetate; toluene;

Reference yield:

: 89793-09-9
2-chloro-3-nitro-4,6-dimethyl-pyridine

: 415907-59-4
2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl propionate

Guidance literature:: Multi-step reaction with 3 steps

1: 3 h / 150 °C

2: hydrogen / palladium 10% on activated carbon / ethyl acetate / 6 h / 20 °C

3: toluene / 2 h / 0 °C / Heating / reflux

With hydrogen; palladium 10% on activated carbon; In ethyl acetate; toluene;