[3-(acetoxy)-2,6-dimethylphenyl](3-isopropyl-4,5-dimethoxyphenyl)methyl acetate

Base Information

• Chemical Name: [3-(acetoxy)-2,6-dimethylphenyl](3-isopropyl-4,5-dimethoxyphenyl)methyl acetate
• CAS No.: 1357476-76-6
• Molecular Formula: C₂₄H₃₀O₆
• Molecular Weight: 414.499
• Mol file: 1357476-76-6.mol

Synonyms:[3-(acetoxy)-2,6-dimethylphenyl](3-isopropyl-4,5-dimethoxyphenyl)methyl acetate

Chemical Property of [3-(acetoxy)-2,6-dimethylphenyl](3-isopropyl-4,5-dimethoxyphenyl)methyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [3-(acetoxy)-2,6-dimethylphenyl](3-isopropyl-4,5-dimethoxyphenyl)methyl acetate

There total 7 articles about [3-(acetoxy)-2,6-dimethylphenyl](3-isopropyl-4,5-dimethoxyphenyl)methyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-[hydroxy(3-isopropyl-4,5-dimethoxyphenyl)methyl]-2,4-dimethylphenol (1357476-75-5) + acetyl chloride (75-36-5) → [3-(acetoxy)-2,6-dimethylphenyl](3-isopropyl-4,5-dimethoxyphenyl)methyl acetate (1357476-76-6)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 14h;

DOI:10.1080/00397911.2010.518274

Reference yield:

3-[hydroxy(3-isopropenyl-4,5-dimethoxyphenyl)methyl]-2,4-dimethylphenol (1357476-73-3) → [3-(acetoxy)-2,6-dimethylphenyl](3-isopropyl-4,5-dimethoxyphenyl)methyl acetate (1357476-76-6)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / methanol / 16 h / 20 °C / 760.05 Torr

2: triethylamine / dichloromethane / 14 h / 0 - 20 °C

With palladium 10% on activated carbon; hydrogen; triethylamine; In methanol; dichloromethane;

DOI:10.1080/00397911.2010.518274

Reference yield:

C26H38O4Si (1357476-72-2) → [3-(acetoxy)-2,6-dimethylphenyl](3-isopropyl-4,5-dimethoxyphenyl)methyl acetate (1357476-76-6)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 0 - 20 °C

2: palladium 10% on activated carbon; hydrogen / methanol / 16 h / 20 °C / 760.05 Torr

3: triethylamine / dichloromethane / 14 h / 0 - 20 °C

With palladium 10% on activated carbon; tetrabutyl ammonium fluoride; hydrogen; triethylamine; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1080/00397911.2010.518274

upstream raw materials:

C₂₆H₃₈O₄Si

3-[hydroxy(3-isopropenyl-4,5-dimethoxyphenyl)methyl]-2,4-dimethylphenol

3-[hydroxy(3-isopropyl-4,5-dimethoxyphenyl)methyl]-2,4-dimethylphenol

acetyl chloride

Downstream raw materials:

3-[(acetoxy)-(2-bromo-3-isopropyl-4,5-dimethoxyphenyl)methyl]-2,4-dimethylphenyl acetate

(2-bromo-3-isopropyl-4,5-dimethoxyphenyl)(3-hydroxy-2,6-dimethylphenyl)methyl acetate

3-[(2-bromo-3-isopropyl-4,5-dimethoxyphenyl)(hydroxy)methyl]-2,4-dimethylphenol

3-[(2-bromo-3-isopropyl-4,5-dimethoxyphenyl)(hydroxy)methyl]-2,4-dimethyl-4-(2,2,2-trifluoroethoxy)cyclohexa-2,5-dien-1-one